Intrapleural administration of Pulmozyme for pleural empyema

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003255" target="_blank" >RIV/00216208:11120/11:00003255 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.rmedc.2010.12.002" target="_blank" >http://dx.doi.org/10.1016/j.rmedc.2010.12.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rmedc.2010.12.002" target="_blank" >10.1016/j.rmedc.2010.12.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Intrapleural administration of Pulmozyme for pleural empyema

Popis výsledku v původním jazyce

Empyema is a severe complication of different diseases and traumas. Management of this complication is difficult and should comprise general and local procedures. The general procedure is mainly based on administering wide-spectrum antibiotics. Local management depends on general condition, but in all cases the essential procedure is inserting a drain into the pleural cavity and evacuation the pus. Sometimes pus is very thick and its evacuation and re-expansion of the lung is rather impossible. In thesepatients surgical procedures are required. The use of intrapleural enzymes to aid drainage was first described in 1949 by Tillett and Sherry using a mixture of streptokinase and streptococcal DNase (deoxyribonuclease).1 In recent years purified streptokinase has come into widespread use, but recent studies suggest that it has no effect on pus viscosity. DNase reduces pus viscosity and may be more useful in treatment.2 We report a case of intrapleural administration of Pulmozyme (alfa do

Název v anglickém jazyce

Intrapleural administration of Pulmozyme for pleural empyema

Popis výsledku anglicky

Empyema is a severe complication of different diseases and traumas. Management of this complication is difficult and should comprise general and local procedures. The general procedure is mainly based on administering wide-spectrum antibiotics. Local management depends on general condition, but in all cases the essential procedure is inserting a drain into the pleural cavity and evacuation the pus. Sometimes pus is very thick and its evacuation and re-expansion of the lung is rather impossible. In thesepatients surgical procedures are required. The use of intrapleural enzymes to aid drainage was first described in 1949 by Tillett and Sherry using a mixture of streptokinase and streptococcal DNase (deoxyribonuclease).1 In recent years purified streptokinase has come into widespread use, but recent studies suggest that it has no effect on pus viscosity. DNase reduces pus viscosity and may be more useful in treatment.2 We report a case of intrapleural administration of Pulmozyme (alfa do

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Respiratory Medicine CME

ISSN

1755-0017

e-ISSN

—

Svazek periodika

4

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

2

Strana od-do

114-115

Kód UT WoS článku

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EID výsledku v databázi Scopus

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