Human papillomavirus genotype distribution in Czech women and men with diseases etiologically linked to HPV
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003338" target="_blank" >RIV/00216208:11120/11:00003338 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11130/11:7039 RIV/00064173:_____/11:#0000288 RIV/00064203:_____/11:7039 RIV/00023736:_____/11:00009261
Výsledek na webu
<a href="http://dx.doi.org/10.1371/journal.pone.0021913" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0021913</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0021913" target="_blank" >10.1371/journal.pone.0021913</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Human papillomavirus genotype distribution in Czech women and men with diseases etiologically linked to HPV
Popis výsledku v původním jazyce
The HPV prevalence and genotype distribution are important for the estimation of the impact of HPV-based cervical cancer screening and HPV vaccination on the incidence of diseases etiologically linked to HPVs. The HPV genotype distribution varies acrossdifferent geographical regions. Therefore, we investigated the type-specific HPV prevalence in Czech women and men with anogenital diseases. We analyzed 157 squamous cell carcinoma samples, 695 precancerous lesion samples and 64 cervical, vulvar and analcondylomata acuminate samples. HPV detection and typing were performed by PCR with GP5+/6+ primers, reverse line blot assay and sequencing. The prevalence of vaccinal and related HPV types in patients with HPV-associated diseases in the Czech Republic is very high. We may assume that the implementation of routine vaccination against HPV would greatly reduce the burden of HPV-associated diseases in the Czech Republic.
Název v anglickém jazyce
Human papillomavirus genotype distribution in Czech women and men with diseases etiologically linked to HPV
Popis výsledku anglicky
The HPV prevalence and genotype distribution are important for the estimation of the impact of HPV-based cervical cancer screening and HPV vaccination on the incidence of diseases etiologically linked to HPVs. The HPV genotype distribution varies acrossdifferent geographical regions. Therefore, we investigated the type-specific HPV prevalence in Czech women and men with anogenital diseases. We analyzed 157 squamous cell carcinoma samples, 695 precancerous lesion samples and 64 cervical, vulvar and analcondylomata acuminate samples. HPV detection and typing were performed by PCR with GP5+/6+ primers, reverse line blot assay and sequencing. The prevalence of vaccinal and related HPV types in patients with HPV-associated diseases in the Czech Republic is very high. We may assume that the implementation of routine vaccination against HPV would greatly reduce the burden of HPV-associated diseases in the Czech Republic.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EB - Genetika a molekulární biologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NS10656" target="_blank" >NS10656: Typově specifická prevalence HPV ve screeningové populaci žen</a><br>
Návaznosti
R - Projekt Ramcoveho programu EK
Ostatní
Rok uplatnění
2011
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Plos One
ISSN
1932-6203
e-ISSN
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Svazek periodika
6
Číslo periodika v rámci svazku
7
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
8
Strana od-do
1-8
Kód UT WoS článku
000292781500021
EID výsledku v databázi Scopus
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