Acute bronchitis therapy with ivy leaves extracts in a two-arm study: A double-blind, randomised study vs. an other ivy leaves extract

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003464" target="_blank" >RIV/00216208:11120/11:00003464 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/11:#0000424

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.phymed.2011.06.014" target="_blank" >http://dx.doi.org/10.1016/j.phymed.2011.06.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.phymed.2011.06.014" target="_blank" >10.1016/j.phymed.2011.06.014</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Acute bronchitis therapy with ivy leaves extracts in a two-arm study: A double-blind, randomised study vs. an other ivy leaves extract

Popis výsledku v původním jazyce

Ivy leaves extracts are authorised in medicinal products for the treatment of acute bronchitis. Different studies and the long experience on the market show safety and efficacy of this drug. A double-blind, randomised study was conducted to assess the efficacy and tolerability of ivy leaves soft extract with an other ivy leaves extract. 590 patients with acute bronchitis participated in this study. They were treated with test or comparator for 7 days (+/-1). The Bronchitis Severity Score (BSS) decreasedgradually and to a similar extent from Day 1 to Day 7 in both treatment groups. Starting from values of 6.2-6.3 +/- 1.2, the BSS decreased by approximately 4.7-4.9 points until Day 7, so that patients left the study with a mean BSS of 1.4-1.6. The BSS subscales cough, sputum, rhales/rhonchi, chest pain during coughing, and dyspnoea improved to a similar extent in both treatment groups. Overall, 2.7% of patients (per group and overall) experienced an adverse event, all of which were non-

Název v anglickém jazyce

Acute bronchitis therapy with ivy leaves extracts in a two-arm study: A double-blind, randomised study vs. an other ivy leaves extract

Popis výsledku anglicky

Ivy leaves extracts are authorised in medicinal products for the treatment of acute bronchitis. Different studies and the long experience on the market show safety and efficacy of this drug. A double-blind, randomised study was conducted to assess the efficacy and tolerability of ivy leaves soft extract with an other ivy leaves extract. 590 patients with acute bronchitis participated in this study. They were treated with test or comparator for 7 days (+/-1). The Bronchitis Severity Score (BSS) decreasedgradually and to a similar extent from Day 1 to Day 7 in both treatment groups. Starting from values of 6.2-6.3 +/- 1.2, the BSS decreased by approximately 4.7-4.9 points until Day 7, so that patients left the study with a mean BSS of 1.4-1.6. The BSS subscales cough, sputum, rhales/rhonchi, chest pain during coughing, and dyspnoea improved to a similar extent in both treatment groups. Overall, 2.7% of patients (per group and overall) experienced an adverse event, all of which were non-

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FO - Dermatovenerologie

OECD FORD obor

—

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Phytomedicine

ISSN

0944-7113

e-ISSN

—

Svazek periodika

18

Číslo periodika v rámci svazku

13

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

1105-1109

Kód UT WoS článku

000297187200001

EID výsledku v databázi Scopus

—