The effect of acclimatization and ambient temperature on heat withdrawal threshold in rats

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43908433" target="_blank" >RIV/00216208:11120/15:43908433 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/ejp.515" target="_blank" >http://dx.doi.org/10.1002/ejp.515</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ejp.515" target="_blank" >10.1002/ejp.515</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The effect of acclimatization and ambient temperature on heat withdrawal threshold in rats

Popis výsledku v původním jazyce

Nociception in rats is frequently measured in terms of latency of withdrawal reaction to radiant heat (thermal nociceptive threshold). The aim of this study was to determine how much housing acclimatization and ambient temperature affect the results of thermal pain threshold testing. All experiments used adult male Wistar rats. Thermal pain thresholds were tested using the radiant heat withdrawal reaction at three different body sites: forepaws, hind paws and tail. Skin temperature was measured using anInfrared thermometer and ambient temperature was set at 18, 20, 24 or 26 °C. The results demonstrate that (1) thermal pain threshold was inversely related to both ambient and skin temperature; (2) housing acclimatization and repeated testing had no effect on nociceptive thresholds at any of the three body sites; (3) a resting, cranio-caudal distribution, of nociceptive sensitivity was observed; (4) hind paws and tail were more sensitive to changes of skin and ambient temperature than fo

Název v anglickém jazyce

The effect of acclimatization and ambient temperature on heat withdrawal threshold in rats

Popis výsledku anglicky

Nociception in rats is frequently measured in terms of latency of withdrawal reaction to radiant heat (thermal nociceptive threshold). The aim of this study was to determine how much housing acclimatization and ambient temperature affect the results of thermal pain threshold testing. All experiments used adult male Wistar rats. Thermal pain thresholds were tested using the radiant heat withdrawal reaction at three different body sites: forepaws, hind paws and tail. Skin temperature was measured using anInfrared thermometer and ambient temperature was set at 18, 20, 24 or 26 °C. The results demonstrate that (1) thermal pain threshold was inversely related to both ambient and skin temperature; (2) housing acclimatization and repeated testing had no effect on nociceptive thresholds at any of the three body sites; (3) a resting, cranio-caudal distribution, of nociceptive sensitivity was observed; (4) hind paws and tail were more sensitive to changes of skin and ambient temperature than fo

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT14484" target="_blank" >NT14484: Kombinace opioidních analgetik a psychostimulancií v léčbě chronické bolesti</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Pain

ISSN

1090-3801

e-ISSN

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Svazek periodika

19

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

21-27

Kód UT WoS článku

000346698600005

EID výsledku v databázi Scopus

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