Motor programme activating therapy influences adaptive brain functions in multiple sclerosis: clinical and MRI study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909032" target="_blank" >RIV/00216208:11120/15:43909032 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023001:_____/15:00059113 RIV/00064173:_____/15:N0000032

Výsledek na webu

<a href="http://dx.doi.org/10.1097/MRR.0000000000000090" target="_blank" >http://dx.doi.org/10.1097/MRR.0000000000000090</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MRR.0000000000000090" target="_blank" >10.1097/MRR.0000000000000090</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Motor programme activating therapy influences adaptive brain functions in multiple sclerosis: clinical and MRI study

Popis výsledku v původním jazyce

There is still little scientific evidence for the efficacy of neurofacilitation approaches and their possible influence on brain plasticity and adaptability. In this study, the outcome of a new kind of neurofacilitation approach, motor programme activating therapy (MPAT), was evaluated on the basis of a set of clinical functions and with MRI. Eighteen patients were examined four times with standardized clinical tests and diffusion tensor imaging to monitor changes without therapy, immediately after therapy and 1 month after therapy. Moreover, the strength of effective connectivity was analysed before and after therapy. Patients underwent a 1-h session of MPAT twice a week for 2 months. The data were analysed by nonparametric tests of association and were subsequently statistically evaluated. The therapy led to significant improvement in clinical functions, significant increment of fractional anisotropy and significant decrement of mean diffusivity, and decrement of effective connectivi

Název v anglickém jazyce

Motor programme activating therapy influences adaptive brain functions in multiple sclerosis: clinical and MRI study

Popis výsledku anglicky

There is still little scientific evidence for the efficacy of neurofacilitation approaches and their possible influence on brain plasticity and adaptability. In this study, the outcome of a new kind of neurofacilitation approach, motor programme activating therapy (MPAT), was evaluated on the basis of a set of clinical functions and with MRI. Eighteen patients were examined four times with standardized clinical tests and diffusion tensor imaging to monitor changes without therapy, immediately after therapy and 1 month after therapy. Moreover, the strength of effective connectivity was analysed before and after therapy. Patients underwent a 1-h session of MPAT twice a week for 2 months. The data were analysed by nonparametric tests of association and were subsequently statistically evaluated. The therapy led to significant improvement in clinical functions, significant increment of fractional anisotropy and significant decrement of mean diffusivity, and decrement of effective connectivi

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Rehabilitation Research

ISSN

0342-5282

e-ISSN

—

Svazek periodika

38

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

49-54

Kód UT WoS článku

000349395900006

EID výsledku v databázi Scopus

—