The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909571" target="_blank" >RIV/00216208:11120/15:43909571 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1186/s13098-015-0018-3" target="_blank" >http://dx.doi.org/10.1186/s13098-015-0018-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13098-015-0018-3" target="_blank" >10.1186/s13098-015-0018-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

Popis výsledku v původním jazyce

Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally, irregular sleep, shift work and travelling across time zones lead to disruption of circadian rhythms and asynchrony between the master hypothalamic clock and pacemakers in peripheral tissues. Furthermore, obstructive sleep apnea syndrome (OSA), which affects 4 - 15% of the population, is not only characterized by impairedsleep architecture but also by repetitive hemoglobin desaturations during sleep. Epidemiological studies have identified impaired sleep as an independent risk factor for all cause of-, as well as for cardiovascular, mortality/morbidity. More recently, sleep abnormalities were causally linked to impairments in glucose homeostasis, metabolic syndrome and Type 2 Diabetes Mellitus (T2DM). This review summarized current knowledge on the metabolic alterations associated with the most prevalent

Název v anglickém jazyce

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

Popis výsledku anglicky

Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally, irregular sleep, shift work and travelling across time zones lead to disruption of circadian rhythms and asynchrony between the master hypothalamic clock and pacemakers in peripheral tissues. Furthermore, obstructive sleep apnea syndrome (OSA), which affects 4 - 15% of the population, is not only characterized by impairedsleep architecture but also by repetitive hemoglobin desaturations during sleep. Epidemiological studies have identified impaired sleep as an independent risk factor for all cause of-, as well as for cardiovascular, mortality/morbidity. More recently, sleep abnormalities were causally linked to impairments in glucose homeostasis, metabolic syndrome and Type 2 Diabetes Mellitus (T2DM). This review summarized current knowledge on the metabolic alterations associated with the most prevalent

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

<a href="/cs/project/GA13-27735S" target="_blank" >GA13-27735S: Poruchy v metabolismu tukové tkáně vedoucí k rozvoji diabetu u syndromu spánkové apnoe (Studie SAMET - spánková apnoe a metabolismus tukové tkáně)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Diabetology &amp; Metabolic Syndrome

ISSN

1758-5996

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

-

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

16

Strana od-do

"Article 25"

Kód UT WoS článku

000352068600001

EID výsledku v databázi Scopus

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