Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909862" target="_blank" >RIV/00216208:11120/15:43909862 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/15:#0000483

Výsledek na webu

<a href="http://dx.doi.org/10.1517/14740338.2015.1044970" target="_blank" >http://dx.doi.org/10.1517/14740338.2015.1044970</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1517/14740338.2015.1044970" target="_blank" >10.1517/14740338.2015.1044970</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others

Popis výsledku v původním jazyce

The review presents complications associated with the use of agents containing sodium phosphate with regard to electrolyte disorders and renal impairment, namely acute phosphate nephropathy (APhN). This paper discusses the pathophysiology, histopathological findings, clinical symptoms, diagnosis and treatment of APhN. Additionally, it examines the epidemiology of adverse renal events and the safety of using sodium phosphate preparations prior to colonoscopy. EXPERT OPINION: Because of safety concerns, sodium phosphate purgatives are not recommended for routine bowel cleansing. Despite some serious and even fatal adverse events associated with these drugs when used with at-risk patients, available data suggest that administration of sodium phosphate purgatives is relatively safe in nonrisk individuals(i.e., in adequately hydrated, otherwise healthy adults, younger than 55 years with evidence of normal renal function).

Název v anglickém jazyce

Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others

Popis výsledku anglicky

The review presents complications associated with the use of agents containing sodium phosphate with regard to electrolyte disorders and renal impairment, namely acute phosphate nephropathy (APhN). This paper discusses the pathophysiology, histopathological findings, clinical symptoms, diagnosis and treatment of APhN. Additionally, it examines the epidemiology of adverse renal events and the safety of using sodium phosphate preparations prior to colonoscopy. EXPERT OPINION: Because of safety concerns, sodium phosphate purgatives are not recommended for routine bowel cleansing. Despite some serious and even fatal adverse events associated with these drugs when used with at-risk patients, available data suggest that administration of sodium phosphate purgatives is relatively safe in nonrisk individuals(i.e., in adequately hydrated, otherwise healthy adults, younger than 55 years with evidence of normal renal function).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Expert Opinion on Drug Safety

ISSN

1474-0338

e-ISSN

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Svazek periodika

14

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

1097-1110

Kód UT WoS článku

000357547900008

EID výsledku v databázi Scopus

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