What evidence is there to show which antipsychotics are more diabetogenic than others?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43910367" target="_blank" >RIV/00216208:11120/15:43910367 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

What evidence is there to show which antipsychotics are more diabetogenic than others?

Popis výsledku v původním jazyce

BACKGROUND: The use of antipsychotic therapy has been proven to have an association with the incidence of diabetes mellitus. The use of atypical antipsychotics is shown to have a higher association, in contrast with typical antipsychotics. Olanzapine andClozapine appear to have the highest rates of diabetes mellitus incidence, due to their tendency to affect glucose metabolism compared with other antipsychotic drugs. In this research the main goal is to understand which antipsychotic drugs are the mostdiabetogenic and to show the mechanisms involved in the glucose metabolism dysregulations with special focus on Olanzapine considering it is a very commonly prescribed and used drug especially among patients with schizophrenia. METHODS: Our study is a literature based research. For our research we reviewed 41 Pubmed published articles from 2005 to 2015. CONCLUSION: According to most of the literature, from all the antipsychotics, Clozapine followed by Olanzapine appear to be the atypica

Název v anglickém jazyce

What evidence is there to show which antipsychotics are more diabetogenic than others?

Popis výsledku anglicky

BACKGROUND: The use of antipsychotic therapy has been proven to have an association with the incidence of diabetes mellitus. The use of atypical antipsychotics is shown to have a higher association, in contrast with typical antipsychotics. Olanzapine andClozapine appear to have the highest rates of diabetes mellitus incidence, due to their tendency to affect glucose metabolism compared with other antipsychotic drugs. In this research the main goal is to understand which antipsychotic drugs are the mostdiabetogenic and to show the mechanisms involved in the glucose metabolism dysregulations with special focus on Olanzapine considering it is a very commonly prescribed and used drug especially among patients with schizophrenia. METHODS: Our study is a literature based research. For our research we reviewed 41 Pubmed published articles from 2005 to 2015. CONCLUSION: According to most of the literature, from all the antipsychotics, Clozapine followed by Olanzapine appear to be the atypica

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Psychiatria Danubina

ISSN

0353-5053

e-ISSN

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Svazek periodika

27

Číslo periodika v rámci svazku

Suppl. 1

Stát vydavatele periodika

HR - Chorvatská republika

Počet stran výsledku

6

Strana od-do

"S423"-"S428"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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