Biomarkers of apoptosis, inflammation and cardiac extracellular matrix remodeling in the prognosis of heart failure

Kód výsledku v IS VaVaI

RIV/00216208:11120/17:43912267 - isvavai.cz

Výsledek na webu

http://dx.doi.org/10.5603/KP.a2016.0154

DOI - Digital Object Identifier

10.5603/KP.a2016.0154

Jazyk výsledku

angličtina

Název v původním jazyce

Biomarkers of apoptosis, inflammation and cardiac extracellular matrix remodeling in the prognosis of heart failure

Popis výsledku v původním jazyce

BACKGROUND: Heart failure (HF) belongs to the leading causes of morbidity and mortality. AIM: The aim of the review is to evaluate available literature on biomarkers of apoptosis, extracellular matrix remodelling, and recently established markers of inflammation in patients with HF. METHODS: Using the search words "Fas, "TRAIL", "apoptosis", "heart failure", "galectin-2, "ST-2", "metaloproteinase", "TGF- β1", "prognosis", "coronary artery diseases", and "dilated cardiomyopathy", a search was carried out. RESULTS: Eighty observational studies were included in the review. CONCLUSIONS: The markers of apoptosis TRAIL and the inflammatory marker galectin-3, as well as the GDF-15, seem to be the most promissing biomarkers for the prognosis of patients with heart failure.

Název v anglickém jazyce

Biomarkers of apoptosis, inflammation and cardiac extracellular matrix remodeling in the prognosis of heart failure

Popis výsledku anglicky

BACKGROUND: Heart failure (HF) belongs to the leading causes of morbidity and mortality. AIM: The aim of the review is to evaluate available literature on biomarkers of apoptosis, extracellular matrix remodelling, and recently established markers of inflammation in patients with HF. METHODS: Using the search words "Fas, "TRAIL", "apoptosis", "heart failure", "galectin-2, "ST-2", "metaloproteinase", "TGF- β1", "prognosis", "coronary artery diseases", and "dilated cardiomyopathy", a search was carried out. RESULTS: Eighty observational studies were included in the review. CONCLUSIONS: The markers of apoptosis TRAIL and the inflammatory marker galectin-3, as well as the GDF-15, seem to be the most promissing biomarkers for the prognosis of patients with heart failure.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Kardiologia Polska

ISSN

0022-9032

e-ISSN

—

Svazek periodika

75

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

11

Strana od-do

295-305

Kód UT WoS článku

000399748200001

EID výsledku v databázi Scopus

2-s2.0-85018586858