Clinical outcomes of acute ischemic stroke patients treated by direct catheter-based trombectomy depending on their baseline characteristic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F18%3A43916231" target="_blank" >RIV/00216208:11120/18:43916231 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/18:N0000118

Výsledek na webu

<a href="https://doi.org/10.1016/j.crvasa.2017.12.010" target="_blank" >https://doi.org/10.1016/j.crvasa.2017.12.010</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crvasa.2017.12.010" target="_blank" >10.1016/j.crvasa.2017.12.010</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Clinical outcomes of acute ischemic stroke patients treated by direct catheter-based trombectomy depending on their baseline characteristic

Popis výsledku v původním jazyce

Background: Direct catheter-based thrombectomy (d-CBT) was proven to be an effective treatment for proximal occlusions of the major intracranial arteries in acute stroke patients. The aim of this study was to compare clinical outcomes of patients treated by d-CBT depending on their baseline characteristics. Methods: A single center, prospective, observational registry of consecutive patients (pts) treated by d-CBT for an acute ischemic stroke. The degree of dependence after a stroke was measured by the modified Rankin scale (mRS) at 3 months follow-up and pts were divided into 2 subgroups based on functional independence/dependence (mRS 0-2 vs. 3-6). Results: A total of 111 consecutive patients (mean age 65.9 ys, men 55%) have been enrolled. A favorable outcome (mRS. ≤. 2 at 3 months) was reached in 39.8% (44. pts). The pts with favorable outcome (mRS. ≤. 2) compared to pts with poor outcome (mRS 3-6) were younger (61 ys vs. 70 ys, p &lt;. 0.01), had higher prevalence of cigarette smoking (45.5% vs. 25.4%, p &lt;. 0.002) and had lower prevalence of known atrial fibrilation (25% vs. 53.7%, p &lt;. 0.001). There were no significant differences between the subgroups in: sex (men 50% vs. 58%, p = 0.27), body mass index (27.8 vs. 29.2, p = 21), arterial hypertension (70.5% vs. 77.6%, p = 0.26), diabetes mellitus (15.9% vs. 25.4%, p = 15), chronic kidney disease (11.4% vs. 22.4%, p = 0.08) and NIHSS on admission (15 vs. 18, p = 0.69). Conclusions: Mechanical thrombectomy achieved better clinical results in younger patients, in smokers and in patients with stroke not caused by atrial fibrillation.

Název v anglickém jazyce

Clinical outcomes of acute ischemic stroke patients treated by direct catheter-based trombectomy depending on their baseline characteristic

Popis výsledku anglicky

Background: Direct catheter-based thrombectomy (d-CBT) was proven to be an effective treatment for proximal occlusions of the major intracranial arteries in acute stroke patients. The aim of this study was to compare clinical outcomes of patients treated by d-CBT depending on their baseline characteristics. Methods: A single center, prospective, observational registry of consecutive patients (pts) treated by d-CBT for an acute ischemic stroke. The degree of dependence after a stroke was measured by the modified Rankin scale (mRS) at 3 months follow-up and pts were divided into 2 subgroups based on functional independence/dependence (mRS 0-2 vs. 3-6). Results: A total of 111 consecutive patients (mean age 65.9 ys, men 55%) have been enrolled. A favorable outcome (mRS. ≤. 2 at 3 months) was reached in 39.8% (44. pts). The pts with favorable outcome (mRS. ≤. 2) compared to pts with poor outcome (mRS 3-6) were younger (61 ys vs. 70 ys, p &lt;. 0.01), had higher prevalence of cigarette smoking (45.5% vs. 25.4%, p &lt;. 0.002) and had lower prevalence of known atrial fibrilation (25% vs. 53.7%, p &lt;. 0.001). There were no significant differences between the subgroups in: sex (men 50% vs. 58%, p = 0.27), body mass index (27.8 vs. 29.2, p = 21), arterial hypertension (70.5% vs. 77.6%, p = 0.26), diabetes mellitus (15.9% vs. 25.4%, p = 15), chronic kidney disease (11.4% vs. 22.4%, p = 0.08) and NIHSS on admission (15 vs. 18, p = 0.69). Conclusions: Mechanical thrombectomy achieved better clinical results in younger patients, in smokers and in patients with stroke not caused by atrial fibrillation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cor et Vasa

ISSN

0010-8650

e-ISSN

—

Svazek periodika

60

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

5

Strana od-do

"e30"-"e34"

Kód UT WoS článku

000426976600006

EID výsledku v databázi Scopus

2-s2.0-85040599005