Oxidative stress markers, thioredoxin 1 and 8-isoprostane, in relation to ischemic time in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921778" target="_blank" >RIV/00216208:11120/21:43921778 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/21:N0000054 RIV/00216224:14110/21:00122749

Výsledek na webu

<a href="https://doi.org/10.20452/pamw.16057" target="_blank" >https://doi.org/10.20452/pamw.16057</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.20452/pamw.16057" target="_blank" >10.20452/pamw.16057</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Oxidative stress markers, thioredoxin 1 and 8-isoprostane, in relation to ischemic time in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention

Popis výsledku v původním jazyce

The extent of an ischemia-reperfusion injury (IRI) significantly affects the prognosis of patients with ST-elevations myocardial infarction (STEMI). Excessive generation of reactive oxygen species during ischemia and subsequent reperfusion leads to cellular necrosis and apoptosis. These processes contribute to impairment of microcirculation and the non-reflow phenomenon, development and progression of left ventricular remodeling and failure. Many factors affect the complex process of IRI, out of them ischemia duration is of major importance. Prolonged ischemia has been associated with higher degree of oxidative stress, but only scarce evidence is available up to date. Our goal was to evaluate selected markers of oxidative stress in relation to the reperfusion via primary percutaneous coronary intervention (pPCI) and their potential correlation with the ischemic time: time-delay (TD) from symptom onset to reperfusion.

Název v anglickém jazyce

Oxidative stress markers, thioredoxin 1 and 8-isoprostane, in relation to ischemic time in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention

Popis výsledku anglicky

The extent of an ischemia-reperfusion injury (IRI) significantly affects the prognosis of patients with ST-elevations myocardial infarction (STEMI). Excessive generation of reactive oxygen species during ischemia and subsequent reperfusion leads to cellular necrosis and apoptosis. These processes contribute to impairment of microcirculation and the non-reflow phenomenon, development and progression of left ventricular remodeling and failure. Many factors affect the complex process of IRI, out of them ischemia duration is of major importance. Prolonged ischemia has been associated with higher degree of oxidative stress, but only scarce evidence is available up to date. Our goal was to evaluate selected markers of oxidative stress in relation to the reperfusion via primary percutaneous coronary intervention (pPCI) and their potential correlation with the ischemic time: time-delay (TD) from symptom onset to reperfusion.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polish Archives of Internal Medicine

ISSN

0032-3772

e-ISSN

—

Svazek periodika

131

Číslo periodika v rámci svazku

7-8

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

4

Strana od-do

755-758

Kód UT WoS článku

000700888500028

EID výsledku v databázi Scopus

2-s2.0-85113964225