Unexpected infiltration of meninges by generalised diffuse large B-cell lymphoma manifesting as multiple cranial neuropathies in a patient with history of breast carcinoma - authors' reply

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921833" target="_blank" >RIV/00216208:11120/21:43921833 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.5603/PJNNS.a2021.0049" target="_blank" >https://doi.org/10.5603/PJNNS.a2021.0049</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5603/PJNNS.a2021.0049" target="_blank" >10.5603/PJNNS.a2021.0049</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Unexpected infiltration of meninges by generalised diffuse large B-cell lymphoma manifesting as multiple cranial neuropathies in a patient with history of breast carcinoma - authors' reply

Popis výsledku v původním jazyce

Leptomeningeal spread of malignant tumorous cells occurs more commonly in haematological malignancies (incidence of 10-15%) and less often with solid tumours such as breast cancer, lung cancer, and melanoma (incidence of 1-5%) [1]. Diagnostic methods mainly include clinical assessment, cerebrospinal fluid cytological examinations [2], and magnetic resonance imaging (MRI) to distinguish brain metastases from other brain tumours [3]. We present a case of leptomeningeal malignant infiltration in a patient with known breast carcinoma, that initially presented as multiple cranial neuropathies. Surprisingly, but consistent with previous cerebrospinal fluid (CSF) examinations, the autopsy excluded meningeal carcinomatosis by breast cancer malignant cells, and confirmed generalised B-cell lymphoma, including leptomeningeal infiltration. An 84-year-old female with a history of diabetes, arterial hypertension, and breast cancer diagnosed three years previously and treated by mastectomy and tamoxifen, presented with multiple cranial nerve palsies.

Název v anglickém jazyce

Unexpected infiltration of meninges by generalised diffuse large B-cell lymphoma manifesting as multiple cranial neuropathies in a patient with history of breast carcinoma - authors' reply

Popis výsledku anglicky

Leptomeningeal spread of malignant tumorous cells occurs more commonly in haematological malignancies (incidence of 10-15%) and less often with solid tumours such as breast cancer, lung cancer, and melanoma (incidence of 1-5%) [1]. Diagnostic methods mainly include clinical assessment, cerebrospinal fluid cytological examinations [2], and magnetic resonance imaging (MRI) to distinguish brain metastases from other brain tumours [3]. We present a case of leptomeningeal malignant infiltration in a patient with known breast carcinoma, that initially presented as multiple cranial neuropathies. Surprisingly, but consistent with previous cerebrospinal fluid (CSF) examinations, the autopsy excluded meningeal carcinomatosis by breast cancer malignant cells, and confirmed generalised B-cell lymphoma, including leptomeningeal infiltration. An 84-year-old female with a history of diabetes, arterial hypertension, and breast cancer diagnosed three years previously and treated by mastectomy and tamoxifen, presented with multiple cranial nerve palsies.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30109 - Pathology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neurologia i Neurochirurgia Polska

ISSN

0028-3843

e-ISSN

—

Svazek periodika

55

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

3

Strana od-do

499-501

Kód UT WoS článku

000713329700012

EID výsledku v databázi Scopus

2-s2.0-85119998027