Novel approach to diagnosis of His bundle capture using individualized left ventricular lateral wall activation time as reference

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921940" target="_blank" >RIV/00216208:11120/21:43921940 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/21:N0000084

Výsledek na webu

<a href="https://doi.org/10.1111/jce.15233" target="_blank" >https://doi.org/10.1111/jce.15233</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jce.15233" target="_blank" >10.1111/jce.15233</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Novel approach to diagnosis of His bundle capture using individualized left ventricular lateral wall activation time as reference

Popis výsledku v původním jazyce

BACKGROUND: During non-selective His bundle (HB) pacing, it is clinically important to confirm His bundle capture vs. right ventricular septal (RVS) capture. The present study aimed to validate the hypothesis that during HB capture, left ventricular lateral wall activation time, approximated by the V(6) R-wave peak time (V(6) RWPT), will not be longer than the corresponding activation time during native conduction. METHODS: Consecutive patients with permanent HB pacing were recruited; cases with abnormal His-ventricle interval or left bundle branch block were excluded. Two corresponding intervals were compared: stimulus-V(6) RWPT and native HBpotential-V(6) RWPT. The difference between these two intervals (delta V(6) RWPT), which was diagnostic of lack of HB capture, was identified using receiver operating characteristic (ROC) curve analysis. RESULTS: A total of 723 ECGs (219 with native rhythm, 172 with selective HB, 215 with non-selective HB, and 117 with RVS capture) were obtained from 219 patients. The native HB-V(6) RWPT, non-selective-, and selective-HB paced V(6) RWPT were nearly equal, while RVS V(6) RWPT was 32.0 (+-9.5) ms longer. The ROC curve analysis indicated delta V(6) RWPT &gt; 12 ms as diagnostic of lack of HB capture (specificity of 99.1% and sensitivity of 100%). A blinded observer correctly diagnosed 96.7% (321/332) of ECGs using this criterion. CONCLUSIONS: We validated a novel criterion for HB capture that is based on the physiological left ventricular activation time as an individualized reference. HB capture can be diagnosed when paced V(6) RWPT does not exceed the value obtained during native conduction by more than 12 ms, while longer paced V(6) RWPT indicates RVS capture.

Název v anglickém jazyce

Novel approach to diagnosis of His bundle capture using individualized left ventricular lateral wall activation time as reference

Popis výsledku anglicky

BACKGROUND: During non-selective His bundle (HB) pacing, it is clinically important to confirm His bundle capture vs. right ventricular septal (RVS) capture. The present study aimed to validate the hypothesis that during HB capture, left ventricular lateral wall activation time, approximated by the V(6) R-wave peak time (V(6) RWPT), will not be longer than the corresponding activation time during native conduction. METHODS: Consecutive patients with permanent HB pacing were recruited; cases with abnormal His-ventricle interval or left bundle branch block were excluded. Two corresponding intervals were compared: stimulus-V(6) RWPT and native HBpotential-V(6) RWPT. The difference between these two intervals (delta V(6) RWPT), which was diagnostic of lack of HB capture, was identified using receiver operating characteristic (ROC) curve analysis. RESULTS: A total of 723 ECGs (219 with native rhythm, 172 with selective HB, 215 with non-selective HB, and 117 with RVS capture) were obtained from 219 patients. The native HB-V(6) RWPT, non-selective-, and selective-HB paced V(6) RWPT were nearly equal, while RVS V(6) RWPT was 32.0 (+-9.5) ms longer. The ROC curve analysis indicated delta V(6) RWPT &gt; 12 ms as diagnostic of lack of HB capture (specificity of 99.1% and sensitivity of 100%). A blinded observer correctly diagnosed 96.7% (321/332) of ECGs using this criterion. CONCLUSIONS: We validated a novel criterion for HB capture that is based on the physiological left ventricular activation time as an individualized reference. HB capture can be diagnosed when paced V(6) RWPT does not exceed the value obtained during native conduction by more than 12 ms, while longer paced V(6) RWPT indicates RVS capture.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Cardiovascular Electrophysiology

ISSN

1045-3873

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

3010-3018

Kód UT WoS článku

000692640400001

EID výsledku v databázi Scopus

2-s2.0-85114103985