Re: Vertebral osteomyelitis in bacterial meningitis patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F22%3A43922661" target="_blank" >RIV/00216208:11120/22:43922661 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.ijid.2021.11.044" target="_blank" >https://doi.org/10.1016/j.ijid.2021.11.044</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijid.2021.11.044" target="_blank" >10.1016/j.ijid.2021.11.044</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Re: Vertebral osteomyelitis in bacterial meningitis patients

Popis výsledku v původním jazyce

I read with interest the original report &quot;Vertebral osteomyelitis in bacterial meningitis patients&quot; (Sheybani et al., 2021). The authors pointed out the possible coexistence of acute bacterial meningitis (ABM) and vertebral osteomyelitis (VO), or infective endocarditis, and the need for longer duration of antimicrobial treatment in such cases. That is correct. However, the hypothesis that VO is a complication of ABM is rather incorrect. VO is caused in most cases by hematogenous dissemination of infection, rarely by contiguous spread from adjacent soft tissue infection, retroperitoneum or pelvis. Infectious inflammation of the vertebral body, disc and facet joint develops for weeks to months before it manifests clinically. Leptomeningeal infection develops only a few hours to days until the onset of clinical symptoms. Thus, in terms of time, meningitis is very unlikely to be the cause of osteomyelitis. The fact that osteomyelitis was diagnosed a few days after the diagnosis of meningitis does not confirm the time scenario meningitis first and then osteomyelitis. The probable sequence in most cases is at first spondylodiscitis that induces meningitis, initially spinal followed by cranial meninges involvement. The authors also hypothesize that a parameningeal infectious focus may elicit an inflammatory response of leptomeninges. That is true but such infectious foci (abscesses) mostly result from local extension of infection from vertebra or disc.

Název v anglickém jazyce

Re: Vertebral osteomyelitis in bacterial meningitis patients

Popis výsledku anglicky

I read with interest the original report &quot;Vertebral osteomyelitis in bacterial meningitis patients&quot; (Sheybani et al., 2021). The authors pointed out the possible coexistence of acute bacterial meningitis (ABM) and vertebral osteomyelitis (VO), or infective endocarditis, and the need for longer duration of antimicrobial treatment in such cases. That is correct. However, the hypothesis that VO is a complication of ABM is rather incorrect. VO is caused in most cases by hematogenous dissemination of infection, rarely by contiguous spread from adjacent soft tissue infection, retroperitoneum or pelvis. Infectious inflammation of the vertebral body, disc and facet joint develops for weeks to months before it manifests clinically. Leptomeningeal infection develops only a few hours to days until the onset of clinical symptoms. Thus, in terms of time, meningitis is very unlikely to be the cause of osteomyelitis. The fact that osteomyelitis was diagnosed a few days after the diagnosis of meningitis does not confirm the time scenario meningitis first and then osteomyelitis. The probable sequence in most cases is at first spondylodiscitis that induces meningitis, initially spinal followed by cranial meninges involvement. The authors also hypothesize that a parameningeal infectious focus may elicit an inflammatory response of leptomeninges. That is true but such infectious foci (abscesses) mostly result from local extension of infection from vertebra or disc.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Infectious Diseases

ISSN

1201-9712

e-ISSN

1878-3511

Svazek periodika

115

Číslo periodika v rámci svazku

February

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

217

Kód UT WoS článku

000787774100035

EID výsledku v databázi Scopus

2-s2.0-85122130459