Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F09%3A5529" target="_blank" >RIV/00216208:11130/09:5529 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/09:5529

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response

Popis výsledku v původním jazyce

The primary function of the immune system is to protect the host against pathogens.Success of vaccination diseases has led to efforts to develop strategies to activate a specific immune response against cancer. However,this task has proved to be very challenging.In the last few years there has been rapid progress in the identification of the molecular mechanisms by which the immune system detects pathogens and initiates immune responses. By contrast, recognition of neoplastic cells lags behind, and induction of specific anti-tumour immunity is even less understood.In this chapter we discuss evidence for the role of the immune system in the control of tumour growth. We also rewiev recent advances in the understanding of mechanisms that can alert the immune system ti the presence of neoplastic lesions, and we discuss recent data on the immunogenicity of tumour cells and their interaction with presenting cells.

Název v anglickém jazyce

Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response

Popis výsledku anglicky

The primary function of the immune system is to protect the host against pathogens.Success of vaccination diseases has led to efforts to develop strategies to activate a specific immune response against cancer. However,this task has proved to be very challenging.In the last few years there has been rapid progress in the identification of the molecular mechanisms by which the immune system detects pathogens and initiates immune responses. By contrast, recognition of neoplastic cells lags behind, and induction of specific anti-tumour immunity is even less understood.In this chapter we discuss evidence for the role of the immune system in the control of tumour growth. We also rewiev recent advances in the understanding of mechanisms that can alert the immune system ti the presence of neoplastic lesions, and we discuss recent data on the immunogenicity of tumour cells and their interaction with presenting cells.

Druh

C - Kapitola v odborné knize

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA310%2F08%2F0838" target="_blank" >GA310/08/0838: Příprava vakcín založených na dendritických buňkách pro protinádorovou imunoterapii karcinomu ovaria</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Phagocytosis of Dying Cells: From Molecular Mechanism to Human Disease

ISBN

978-1-4020-9292-3

Počet stran výsledku

24

Strana od-do

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Počet stran knihy

447

Název nakladatele

Springer

Místo vydání

Belgie

Kód UT WoS kapitoly

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