Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F09%3A5568" target="_blank" >RIV/00216208:11130/09:5568 - isvavai.cz</a>
Výsledek na webu
—
DOI - Digital Object Identifier
—

Jazyk výsledku
angličtina
Název v původním jazyce
Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
Popis výsledku v původním jazyce
Shb (an adapter protein)functions in the VEGF signalization. The present study was performed to address endothelial function in the Shb knockout mouse and its relevance for tumor angiogenesis. Tumor growth was retarded in Shb mutated mice and this was correlated with decreased tumor angiogenesis. It is concluded that Shb plays an important role in mouse angiogenesis and Shb signaling may provide novel means to regulate tumor angiogenesis.
Název v anglickém jazyce
Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
Popis výsledku anglicky
Shb (an adapter protein)functions in the VEGF signalization. The present study was performed to address endothelial function in the Shb knockout mouse and its relevance for tumor angiogenesis. Tumor growth was retarded in Shb mutated mice and this was correlated with decreased tumor angiogenesis. It is concluded that Shb plays an important role in mouse angiogenesis and Shb signaling may provide novel means to regulate tumor angiogenesis.

Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FD - Onkologie a hematologie
OECD FORD obor
—

Rok uplatnění
2009
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Podobné výsledky(10)