Localizing value of ictal SPECT is comparable to MRI and EEG in children with focal cortical dysplasia
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10193735" target="_blank" >RIV/00216208:11130/13:10193735 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00064203:_____/13:10193735
Výsledek na webu
<a href="http://dx.doi.org/10.1111/epi.12059" target="_blank" >http://dx.doi.org/10.1111/epi.12059</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/epi.12059" target="_blank" >10.1111/epi.12059</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Localizing value of ictal SPECT is comparable to MRI and EEG in children with focal cortical dysplasia
Popis výsledku v původním jazyce
Purpose To assess the predictive value of ictal single-photon emission computed tomography (SPECT) for outcome after excisional epilepsy surgery in a large population of children with focal cortical dysplasia (FCD). Methods One hundred seventy-three ictal SPECT studies in 106 children with histologically proven FCD were retrospectively analyzed. The extent and location of ictal hyperperfusion and completeness of surgical removal were assessed. Completeness of resection of epileptogenic regions defined by ictal SPECT, electroencephalography (EEG), and magnetic resonance imaging (MRI) were compared and correlated with postoperative seizure outcome. In addition, subcortical activation of the cerebellum, basal ganglia, and thalamus were analyzed. Key Findings The extent of hyperperfusion was focal or lobar in 58%, whereas multilobar activations occurred in only 32%; hemispheric or bilateral findings were rare. Favorable postsurgical seizure outcome was achieved in 67% patients with nonloca
Název v anglickém jazyce
Localizing value of ictal SPECT is comparable to MRI and EEG in children with focal cortical dysplasia
Popis výsledku anglicky
Purpose To assess the predictive value of ictal single-photon emission computed tomography (SPECT) for outcome after excisional epilepsy surgery in a large population of children with focal cortical dysplasia (FCD). Methods One hundred seventy-three ictal SPECT studies in 106 children with histologically proven FCD were retrospectively analyzed. The extent and location of ictal hyperperfusion and completeness of surgical removal were assessed. Completeness of resection of epileptogenic regions defined by ictal SPECT, electroencephalography (EEG), and magnetic resonance imaging (MRI) were compared and correlated with postoperative seizure outcome. In addition, subcortical activation of the cerebellum, basal ganglia, and thalamus were analyzed. Key Findings The extent of hyperperfusion was focal or lobar in 58%, whereas multilobar activations occurred in only 32%; hemispheric or bilateral findings were rare. Favorable postsurgical seizure outcome was achieved in 67% patients with nonloca
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/ME09042" target="_blank" >ME09042: Zhodnocení významu iktálního SPECT v diagnostice kandidátů chirurgické léčby epilepsie</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Epilepsia
ISSN
0013-9580
e-ISSN
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Svazek periodika
54
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
8
Strana od-do
351-358
Kód UT WoS článku
000314750200019
EID výsledku v databázi Scopus
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