Menopausal transition enhances the atherogenic risk of smoking in middle aged women

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10209633" target="_blank" >RIV/00216208:11130/13:10209633 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/13:10209633 RIV/00023001:_____/13:00057609

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ijcard.2012.09.095" target="_blank" >http://dx.doi.org/10.1016/j.ijcard.2012.09.095</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijcard.2012.09.095" target="_blank" >10.1016/j.ijcard.2012.09.095</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Menopausal transition enhances the atherogenic risk of smoking in middle aged women

Popis výsledku v původním jazyce

Background: The presence of cardiovascular risk factors during the menopausal transition could be critical in the development of atherosclerosis. In the present study, we evaluated whether the menopausal transition has impact on traditional and newly discussed risk factors. Methods: Six hundred ninety nine women from population-based study underwent ultrasound measurement of the intima-media thickness of the common carotid arteries (CIMT) - Prague Pre and Postmenopausal Females study (3PMFs). In addition, 40 women selected according to reproductive and smoking status were examined with regard to number of circulating endothelial progenitor cells, markers of reverse cholesterol transport and sex hormones, including their fluctuation - Hormone Variability study (HVs). Results: Age, smoking, body mass index, systolic blood pressure and HDL cholesterol were independently associated with the CIMT in 3PMFs group. The increase in the CIMT with age was markedly steeper in current/past smokers

Název v anglickém jazyce

Menopausal transition enhances the atherogenic risk of smoking in middle aged women

Popis výsledku anglicky

Background: The presence of cardiovascular risk factors during the menopausal transition could be critical in the development of atherosclerosis. In the present study, we evaluated whether the menopausal transition has impact on traditional and newly discussed risk factors. Methods: Six hundred ninety nine women from population-based study underwent ultrasound measurement of the intima-media thickness of the common carotid arteries (CIMT) - Prague Pre and Postmenopausal Females study (3PMFs). In addition, 40 women selected according to reproductive and smoking status were examined with regard to number of circulating endothelial progenitor cells, markers of reverse cholesterol transport and sex hormones, including their fluctuation - Hormone Variability study (HVs). Results: Age, smoking, body mass index, systolic blood pressure and HDL cholesterol were independently associated with the CIMT in 3PMFs group. The increase in the CIMT with age was markedly steeper in current/past smokers

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

<a href="/cs/project/NS10511" target="_blank" >NS10511: Vliv reprodukčního věku na citlivost cévní stěny k zevním, metabolickým a genetickým kardiovaskulárním rizikovým faktorům, longitudinální populační studie.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Cardiology

ISSN

0167-5273

e-ISSN

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Svazek periodika

168

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

7

Strana od-do

190-196

Kód UT WoS článku

000325409800044

EID výsledku v databázi Scopus

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