Predictors of Survival in Patients With Soft Tissue Surgical Margin Involvement at Radical Cystectomy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10209772" target="_blank" >RIV/00216208:11130/13:10209772 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/13:10209772

Výsledek na webu

<a href="http://dx.doi.org/10.1245/s10434-012-2708-5" target="_blank" >http://dx.doi.org/10.1245/s10434-012-2708-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1245/s10434-012-2708-5" target="_blank" >10.1245/s10434-012-2708-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Predictors of Survival in Patients With Soft Tissue Surgical Margin Involvement at Radical Cystectomy

Popis výsledku v původním jazyce

The presence of positive soft tissue surgical margins (STSM) at radical cystectomy (RC) is rare. Although some patients with STSM experience disease recurrence rapidly, some have long-term local disease control. We sought to describe the oncologic outcomes, identify predictors, and assess the impact of location and multifocality in patients with positive STSMs at RC. We retrospectively collected the data of 4,335 patients treated with RC and pelvic lymphadenectomy at 11 academic centers from 1981 to 2008. STSM was defined as the presence of tumor at inked areas of soft tissue on the RC specimen. Univariate and multivariate Cox regression models addressed recurrence-free survival and cancer-specific survival after surgery. STSM were identified in 231 patients (5 %). Actuarial recurrence-free survival estimates at 2 and 5 years after RC were 26 +/- A 3 and 21 +/- A 3 %, respectively. Actuarial cancer-specific survival estimates at 2 and 5 years after RC were 33 +/- A 3 and 25 +/- A 4 %,

Název v anglickém jazyce

Predictors of Survival in Patients With Soft Tissue Surgical Margin Involvement at Radical Cystectomy

Popis výsledku anglicky

The presence of positive soft tissue surgical margins (STSM) at radical cystectomy (RC) is rare. Although some patients with STSM experience disease recurrence rapidly, some have long-term local disease control. We sought to describe the oncologic outcomes, identify predictors, and assess the impact of location and multifocality in patients with positive STSMs at RC. We retrospectively collected the data of 4,335 patients treated with RC and pelvic lymphadenectomy at 11 academic centers from 1981 to 2008. STSM was defined as the presence of tumor at inked areas of soft tissue on the RC specimen. Univariate and multivariate Cox regression models addressed recurrence-free survival and cancer-specific survival after surgery. STSM were identified in 231 patients (5 %). Actuarial recurrence-free survival estimates at 2 and 5 years after RC were 26 +/- A 3 and 21 +/- A 3 %, respectively. Actuarial cancer-specific survival estimates at 2 and 5 years after RC were 33 +/- A 3 and 25 +/- A 4 %,

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annals of Surgical Oncology

ISSN

1068-9265

e-ISSN

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Svazek periodika

20

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1027-1034

Kód UT WoS článku

000314998000044

EID výsledku v databázi Scopus

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