Impact of retransfusion of blood processed in cell-saver on coagulation versus cardiopulmonary bypass: A prospective observational study using thromboelastography

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10294909" target="_blank" >RIV/00216208:11130/15:10294909 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/15:10294909

Výsledek na webu

<a href="http://dx.doi.org/10.5507/bp.2013.012" target="_blank" >http://dx.doi.org/10.5507/bp.2013.012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2013.012" target="_blank" >10.5507/bp.2013.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of retransfusion of blood processed in cell-saver on coagulation versus cardiopulmonary bypass: A prospective observational study using thromboelastography

Popis výsledku v původním jazyce

Aims. To compare an impact of retransfusion of blood processed in cell-saver (CS) with that of cardiopulmonary bypass (CPB) on blood coagulation in patients undergoing cardiac surgery. Methods. Prospective observational study using thromboelastography (TEG). Results. TEG samples from 170 patients were analyzed. Cardiopulmonary bypass was used in 100 patients while 70 patients were operated off-pump. In 20 off-pump patients collected blood was processed by cell-saver and returned. In all patients clot formation after heparin neutralization by protamine was unimpaired. However, there was a significant increase in fibrinolysis defined by the TEG parameter Lysis time 30 min after the maximum amplitude of the clot was reached (Ly30) in groups with CPB or CSbut this increase still did not exceed the threshold for clinical fibrinolysis (Ly30 > 7.5%). In the group without CPB there was no significant impact on coagulation. Conclusion. Surgery that avoids CPB and/or CS is the gentlest method f

Název v anglickém jazyce

Impact of retransfusion of blood processed in cell-saver on coagulation versus cardiopulmonary bypass: A prospective observational study using thromboelastography

Popis výsledku anglicky

Aims. To compare an impact of retransfusion of blood processed in cell-saver (CS) with that of cardiopulmonary bypass (CPB) on blood coagulation in patients undergoing cardiac surgery. Methods. Prospective observational study using thromboelastography (TEG). Results. TEG samples from 170 patients were analyzed. Cardiopulmonary bypass was used in 100 patients while 70 patients were operated off-pump. In 20 off-pump patients collected blood was processed by cell-saver and returned. In all patients clot formation after heparin neutralization by protamine was unimpaired. However, there was a significant increase in fibrinolysis defined by the TEG parameter Lysis time 30 min after the maximum amplitude of the clot was reached (Ly30) in groups with CPB or CSbut this increase still did not exceed the threshold for clinical fibrinolysis (Ly30 > 7.5%). In the group without CPB there was no significant impact on coagulation. Conclusion. Surgery that avoids CPB and/or CS is the gentlest method f

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Svazek periodika

159

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

131-134

Kód UT WoS článku

000351716500021

EID výsledku v databázi Scopus

2-s2.0-84924519854