Abnormalities in pulmonary function in infants with high-risk congenital diaphragmatic hernia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316093" target="_blank" >RIV/00216208:11130/15:10316093 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/15:43910302 RIV/00064203:_____/15:10316093 RIV/00023698:_____/15:#0000186

Výsledek na webu

<a href="http://dx.doi.org/10.5507/bp.2015.040" target="_blank" >http://dx.doi.org/10.5507/bp.2015.040</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2015.040" target="_blank" >10.5507/bp.2015.040</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Abnormalities in pulmonary function in infants with high-risk congenital diaphragmatic hernia

Popis výsledku v původním jazyce

Aims. The aim of the study was to analyze lung growth and abnormality of infant pulmonary function tests (IPFT) in congenital diaphragmatic hernia (CDH) survivors younger than three years of age with respect to unfavorable prognostic factors. Methods. Thirty high-risk CDH survivors at the age of 1.32 +/- 0.54 years, body weight 9.76 +/- 1.25 kg were examined using IPFT: tidal breathing analysis, baby resistance/compliance, whole baby body plethysmography and rapid thoracoabdominal compression. Gore-Texpatch was used in 13% of patients (GORE group). Pulmonary hypertension was diagnosed and managed in 13% (iNO group). Standard protocols and appropriate reference values were used and obtained data were statistically analysed. Results. High incidence of peripheral airway obstruction (70%), increased value of functional residual capacity (FRCp) 191.3 +/- 24.5 mL (126.5 +/- 36.9 % predicted; P < 0.0005), increased value of effective airway resistance (R-eff) 1.71 +/- 0.93 kPa.L-1.s (144.4 +

Název v anglickém jazyce

Abnormalities in pulmonary function in infants with high-risk congenital diaphragmatic hernia

Popis výsledku anglicky

Aims. The aim of the study was to analyze lung growth and abnormality of infant pulmonary function tests (IPFT) in congenital diaphragmatic hernia (CDH) survivors younger than three years of age with respect to unfavorable prognostic factors. Methods. Thirty high-risk CDH survivors at the age of 1.32 +/- 0.54 years, body weight 9.76 +/- 1.25 kg were examined using IPFT: tidal breathing analysis, baby resistance/compliance, whole baby body plethysmography and rapid thoracoabdominal compression. Gore-Texpatch was used in 13% of patients (GORE group). Pulmonary hypertension was diagnosed and managed in 13% (iNO group). Standard protocols and appropriate reference values were used and obtained data were statistically analysed. Results. High incidence of peripheral airway obstruction (70%), increased value of functional residual capacity (FRCp) 191.3 +/- 24.5 mL (126.5 +/- 36.9 % predicted; P < 0.0005), increased value of effective airway resistance (R-eff) 1.71 +/- 0.93 kPa.L-1.s (144.4 +

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FC - Pneumologie

OECD FORD obor

—

Projekt

<a href="/cs/project/NT11444" target="_blank" >NT11444: Časné projevy průduškového astmatu u dětí - funkční a morfologické důsledky nemoci</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Svazek periodika

159

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

497-502

Kód UT WoS článku

000364948100026

EID výsledku v databázi Scopus

2-s2.0-84942919664