Lymphogranuloma venereum with only proximal rectal involvement mimicking inflammatory bowel disease: a potential diagnostic pitfall

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10360598" target="_blank" >RIV/00216208:11130/17:10360598 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/17:10360598 RIV/00064211:_____/17:W0000024

Výsledek na webu

<a href="http://onlinelibrary.wiley.com/doi/10.1111/jdv.14050/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/jdv.14050/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jdv.14050" target="_blank" >10.1111/jdv.14050</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lymphogranuloma venereum with only proximal rectal involvement mimicking inflammatory bowel disease: a potential diagnostic pitfall

Popis výsledku v původním jazyce

We are reporting a case of LGV proctocolitis mimicking IBD in the HIV-positive MSM in whom diagnosis was established by LGV biovar-specific bacterial DNA detection from a bowel biopsy specimen despite repeated negative NAAT for C. trachomatis from rectal smears. LGV usually causes diffuse proctitis, but different endoscopic findings were described including multiple mucous ulcers Mucous ulcers without diffuse proctitis are probably less common manifestation. The situation is even more complicated because endoscopic and histological findings in IBD and LGV can be similar, and thus, histological examination alone is not adequate to establish the diagnosis Few reports were published about retrospective testing of bowel biopsy samples for C. trachomatis DNA and LGV serovar in patients with confirmed or suspected LGV. Our case shows that, in patients with ulcers in the proximal rectum, standard rectal swab is likely to fail to identify the disease. In our patients, sampling swab was repeatedly negative as it is normally only about 15 cm long. Whether proximal ulcers without diffuse proctitis are only a rare presentation of the disease or whether these patients are misdiagnosed remains unknown. These patients may be incorrectly diagnosed as having IBD despite standard recommended STI testing.

Název v anglickém jazyce

Lymphogranuloma venereum with only proximal rectal involvement mimicking inflammatory bowel disease: a potential diagnostic pitfall

Popis výsledku anglicky

We are reporting a case of LGV proctocolitis mimicking IBD in the HIV-positive MSM in whom diagnosis was established by LGV biovar-specific bacterial DNA detection from a bowel biopsy specimen despite repeated negative NAAT for C. trachomatis from rectal smears. LGV usually causes diffuse proctitis, but different endoscopic findings were described including multiple mucous ulcers Mucous ulcers without diffuse proctitis are probably less common manifestation. The situation is even more complicated because endoscopic and histological findings in IBD and LGV can be similar, and thus, histological examination alone is not adequate to establish the diagnosis Few reports were published about retrospective testing of bowel biopsy samples for C. trachomatis DNA and LGV serovar in patients with confirmed or suspected LGV. Our case shows that, in patients with ulcers in the proximal rectum, standard rectal swab is likely to fail to identify the disease. In our patients, sampling swab was repeatedly negative as it is normally only about 15 cm long. Whether proximal ulcers without diffuse proctitis are only a rare presentation of the disease or whether these patients are misdiagnosed remains unknown. These patients may be incorrectly diagnosed as having IBD despite standard recommended STI testing.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30216 - Dermatology and venereal diseases

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the European Academy of Dermatology and Venereology

ISSN

0926-9959

e-ISSN

—

Svazek periodika

31

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

2

Strana od-do

"e264"-"e265"

Kód UT WoS článku

000400188900024

EID výsledku v databázi Scopus

2-s2.0-85008255634