The Interest of Women with Mayer-Rokitansky-Kuster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus Transplantation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F18%3A10378539" target="_blank" >RIV/00216208:11130/18:10378539 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/18:10378539 RIV/00023001:_____/18:00077108

Výsledek na webu

<a href="https://doi.org/10.1016/j.jpag.2018.04.007" target="_blank" >https://doi.org/10.1016/j.jpag.2018.04.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jpag.2018.04.007" target="_blank" >10.1016/j.jpag.2018.04.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Interest of Women with Mayer-Rokitansky-Kuster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus Transplantation

Popis výsledku v původním jazyce

Study Objective: The goal of this study was to assess a group of women with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome with surgically created neovaginas in the interest of uterus transplantation (UTx) and to recruit the first group of applicants for a UTx trial. Design and Setting: This was an original prospective study using semistructured interviews. Participants: A study group of 50 women with MRKH syndrome with Vecchietti neovaginas was recruited via letter of invitation. Interventions and Main Outcome Measures: Interest of MRKH women in obtaining experimental UTx for the treatment of absolute uterine factor infertility. Results: A total of 50 women responded via e-mail and 31 (62% [31 of 50] of the study group) expressed serious interest in UTx after complete information about its risks and benefits was provided during the first semistructured interview. They subsequently agreed to participate in additional interviews and further examinations. Because of various reasons, only 9 women were prepared to enter our UTx trial (18% [9 of 50] of the study group). Three recipients/donors were accepted into the living donor arm and 6 into the deceased brain donor arm of the trial. Conclusion: Nearly two-thirds of our MRKH syndrome study group women with surgically created neovaginas were interested in UTx and motivated to undergo this method of absolute uterine factor infertility treatment. Therefore, this group of women might be approached to participate in ongoing and future UTx trials. Future studies of women with MRKH syndrome might confirm or disprove the results of our survey.

Název v anglickém jazyce

The Interest of Women with Mayer-Rokitansky-Kuster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus Transplantation

Popis výsledku anglicky

Study Objective: The goal of this study was to assess a group of women with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome with surgically created neovaginas in the interest of uterus transplantation (UTx) and to recruit the first group of applicants for a UTx trial. Design and Setting: This was an original prospective study using semistructured interviews. Participants: A study group of 50 women with MRKH syndrome with Vecchietti neovaginas was recruited via letter of invitation. Interventions and Main Outcome Measures: Interest of MRKH women in obtaining experimental UTx for the treatment of absolute uterine factor infertility. Results: A total of 50 women responded via e-mail and 31 (62% [31 of 50] of the study group) expressed serious interest in UTx after complete information about its risks and benefits was provided during the first semistructured interview. They subsequently agreed to participate in additional interviews and further examinations. Because of various reasons, only 9 women were prepared to enter our UTx trial (18% [9 of 50] of the study group). Three recipients/donors were accepted into the living donor arm and 6 into the deceased brain donor arm of the trial. Conclusion: Nearly two-thirds of our MRKH syndrome study group women with surgically created neovaginas were interested in UTx and motivated to undergo this method of absolute uterine factor infertility treatment. Therefore, this group of women might be approached to participate in ongoing and future UTx trials. Future studies of women with MRKH syndrome might confirm or disprove the results of our survey.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Pediatric &amp; Adolescent Gynecology

ISSN

1083-3188

e-ISSN

—

Svazek periodika

31

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

480-484

Kód UT WoS článku

000442913200008

EID výsledku v databázi Scopus

2-s2.0-85049429858