Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F18%3A10393480" target="_blank" >RIV/00216208:11130/18:10393480 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/978-3-319-93485-3_3" target="_blank" >https://doi.org/10.1007/978-3-319-93485-3_3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-319-93485-3_3" target="_blank" >10.1007/978-3-319-93485-3_3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury

Popis výsledku v původním jazyce

Induced pluripotent stem (iPS) cells are derived from differentiated cells by different reprogramming techniques, by introducing specific transcription factors responsible for pluripotency. Induced pluripotent stem cells can serve as an excellent source for differentiated neural stem/progenitor cells (NSCs/NPs). Several methods and protocols are utilized to create a robust number of NSCs/NPs without jeopardizing the safety issues required for in vivo applications. A variety of disease-specific iPS cells have been used to study nervous system diseases. In this chapter, we will focus on some of the derivation and differentiation approaches and the application of iPS-NPs in the treatment of spinal cord injury and stroke. (C) 2018, Springer International Publishing AG, part of Springer Nature.

Název v anglickém jazyce

Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury

Popis výsledku anglicky

Induced pluripotent stem (iPS) cells are derived from differentiated cells by different reprogramming techniques, by introducing specific transcription factors responsible for pluripotency. Induced pluripotent stem cells can serve as an excellent source for differentiated neural stem/progenitor cells (NSCs/NPs). Several methods and protocols are utilized to create a robust number of NSCs/NPs without jeopardizing the safety issues required for in vivo applications. A variety of disease-specific iPS cells have been used to study nervous system diseases. In this chapter, we will focus on some of the derivation and differentiation approaches and the application of iPS-NPs in the treatment of spinal cord injury and stroke. (C) 2018, Springer International Publishing AG, part of Springer Nature.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

<a href="/cs/project/GBP304%2F12%2FG069" target="_blank" >GBP304/12/G069: Projekt excelence v oblasti neurověd</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Human Neural Stem Cells

ISBN

978-3-319-93485-3

Počet stran výsledku

14

Strana od-do

89-102

Počet stran knihy

329

Název nakladatele

Springer Verlag

Místo vydání

Cham

Kód UT WoS kapitoly

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