Lip creams with propolis special extract GH 2002 0.5% versus aciclovir 5.0% for herpes labialis (vesicular stage): Randomized, controlled double-blind study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F19%3A10394538" target="_blank" >RIV/00216208:11130/19:10394538 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=0Sac.WHXh9" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=0Sac.WHXh9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10354-018-0667-6" target="_blank" >10.1007/s10354-018-0667-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lip creams with propolis special extract GH 2002 0.5% versus aciclovir 5.0% for herpes labialis (vesicular stage): Randomized, controlled double-blind study

Popis výsledku v původním jazyce

Alip cream with special propolis extract GH 2002at aconcentration of 0.5% (199 patients) was tested against aciclovir 5% (198 patients) in the treatment of episodes of herpes labialis under double-blind conditions. Upon inclusion, all patients were in the vesicular phase. Application was five times daily of approximately 0.2g of cream to the entire upper and lower lip. The primary parameter was the difference in time between groups to complete encrustation or epithelization of the lesions. Secondary endpoints were the course of typical herpes symptoms (pain, burning and itching, tension and swelling), the global assessment of efficacy and the safety of application. The predefined clinical situation was reached after a(median) 3days with propolis and 4days with aciclovir (p&lt;0.0001). Significant differences in favor of propolis were also found for all secondary parameters. No allergic reactions, local irritations or other adverse events occurred.

Název v anglickém jazyce

Lip creams with propolis special extract GH 2002 0.5% versus aciclovir 5.0% for herpes labialis (vesicular stage): Randomized, controlled double-blind study

Popis výsledku anglicky

Alip cream with special propolis extract GH 2002at aconcentration of 0.5% (199 patients) was tested against aciclovir 5% (198 patients) in the treatment of episodes of herpes labialis under double-blind conditions. Upon inclusion, all patients were in the vesicular phase. Application was five times daily of approximately 0.2g of cream to the entire upper and lower lip. The primary parameter was the difference in time between groups to complete encrustation or epithelization of the lesions. Secondary endpoints were the course of typical herpes symptoms (pain, burning and itching, tension and swelling), the global assessment of efficacy and the safety of application. The predefined clinical situation was reached after a(median) 3days with propolis and 4days with aciclovir (p&lt;0.0001). Significant differences in favor of propolis were also found for all secondary parameters. No allergic reactions, local irritations or other adverse events occurred.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30501 - Forensic science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Wiener Medizinische Wochenschrift

ISSN

0043-5341

e-ISSN

—

Svazek periodika

169

Číslo periodika v rámci svazku

7-8

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

9

Strana od-do

193-201

Kód UT WoS článku

000466985300006

EID výsledku v databázi Scopus

2-s2.0-85056280613