Comparison of outcomes between people with and without central cord syndrome

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F20%3A10411855" target="_blank" >RIV/00216208:11130/20:10411855 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/20:10411855

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=FlFa3QwC3d" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=FlFa3QwC3d</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41393-020-0491-x" target="_blank" >10.1038/s41393-020-0491-x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of outcomes between people with and without central cord syndrome

Popis výsledku v původním jazyce

Study design Retrospective analysis of prospectively collected data. Objective Central cord syndrome (CCS) is reported to have better outcomes than other cervical lesions, especially for ambulation and bladder recovery. However, a formal comparison between patients with CCS and other incomplete cervical spinal cord injuries (iCSCI) is lacking. Aim of the study is to investigate the neurological and functional outcomes in patients with or without CCS. Setting European Multicenter Study. Methods Data following SCI were derived from the European Multicenter Study about Spinal Cord Injury Database. CCS was diagnosed based on a difference of at least ten points of motor score in favour of the lower extremities. Patients were evaluated at 30 days, 6 months and 1 year from injury. The neurological and functional data were collected at each time point based on the International Standards for Neurological Classification of Spinal Cord injury (ISNSCI) and Spinal Cord Independence Measure (SCIM). Patients were selected with a matching procedure based on lesion severity, neurological level of injury (NLI) and age. Evaluation of the outcomes was performed by means of two-way Anova for repeated measures. Results The matching produced 110 comparable dyads. At all time points, upper extremity motor scores remained lower than lower extremity motor scores in CCS compared with iCSCI. With regard to daily life independence, both cohorts achieved comparable improvements in self-care sub-scores between T0 and T2 (6.6 +/- 6.5 in CCS vs 8.2 +/- 6.9 in iCSCI, p = 0.15) but this sub-score was significantly lower in CCS compared with iCSCI (3.6 +/- 5.2 in CCS vs 7.3 +/- 7.0 in iCSCI at T0, 13.7 +/- 6.2 vs 16.5 +/- 5.7 at T2), while the other sub-scores were comparable. Conclusions In contrast to previous reports, people with CCS have poorer outcomes of self-care ability compared with iCSCI.

Název v anglickém jazyce

Comparison of outcomes between people with and without central cord syndrome

Popis výsledku anglicky

Study design Retrospective analysis of prospectively collected data. Objective Central cord syndrome (CCS) is reported to have better outcomes than other cervical lesions, especially for ambulation and bladder recovery. However, a formal comparison between patients with CCS and other incomplete cervical spinal cord injuries (iCSCI) is lacking. Aim of the study is to investigate the neurological and functional outcomes in patients with or without CCS. Setting European Multicenter Study. Methods Data following SCI were derived from the European Multicenter Study about Spinal Cord Injury Database. CCS was diagnosed based on a difference of at least ten points of motor score in favour of the lower extremities. Patients were evaluated at 30 days, 6 months and 1 year from injury. The neurological and functional data were collected at each time point based on the International Standards for Neurological Classification of Spinal Cord injury (ISNSCI) and Spinal Cord Independence Measure (SCIM). Patients were selected with a matching procedure based on lesion severity, neurological level of injury (NLI) and age. Evaluation of the outcomes was performed by means of two-way Anova for repeated measures. Results The matching produced 110 comparable dyads. At all time points, upper extremity motor scores remained lower than lower extremity motor scores in CCS compared with iCSCI. With regard to daily life independence, both cohorts achieved comparable improvements in self-care sub-scores between T0 and T2 (6.6 +/- 6.5 in CCS vs 8.2 +/- 6.9 in iCSCI, p = 0.15) but this sub-score was significantly lower in CCS compared with iCSCI (3.6 +/- 5.2 in CCS vs 7.3 +/- 7.0 in iCSCI at T0, 13.7 +/- 6.2 vs 16.5 +/- 5.7 at T2), while the other sub-scores were comparable. Conclusions In contrast to previous reports, people with CCS have poorer outcomes of self-care ability compared with iCSCI.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30300 - Health sciences

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Spinal Cord

ISSN

1362-4393

e-ISSN

—

Svazek periodika

58

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

1263-1273

Kód UT WoS článku

000537363700002

EID výsledku v databázi Scopus

2-s2.0-85085927485