Reliability of Automated Intracranial Volume Measurements by Synthetic Brain MRI in Children

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F24%3A10481405" target="_blank" >RIV/00216208:11130/24:10481405 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TDM_vciSPk" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TDM_vciSPk</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/app14114751" target="_blank" >10.3390/app14114751</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Reliability of Automated Intracranial Volume Measurements by Synthetic Brain MRI in Children

Popis výsledku v původním jazyce

(1) Background: Hydrocephalus poses challenges in pediatric neuroimaging, and conventional MRI methods have limitations regarding its accurate quantification. Synthetic MRI (SyMRI) offers a promising automated solution to assess intracranial compartment volumes. However, its clinical utility in pediatric patients remains underexplored. Our study aims to assess the accuracy and reliability of automated CSF volume measurements using SyMRI in children and adolescents, comparing them with manual measurements and human expert ratings. (2) Methods: A single-center retrospective study included 124 pediatric patients undergoing cranial MRI with SyMRI. CSF, brain parenchyma, and intracranial volumes were measured using both automated SyMRI and manual methods. Human radiologists assessed hydrocephalus subjectively. (3) Results: Correlations between manual and SyMRI volume evaluations were significant. Human raters demonstrated good agreement on hydrocephalus ratings among themselves (Fleiss&apos; kappa = 0.66, p &lt; 0.001) but only moderate agreement with the SyMRI method (Cohen&apos;s kappa = 0.45, p &lt; 0.001). SyMRI volumes were systematically tendentially higher in SyMRI (CSF p = 0.005; BPV and ICV p &lt; 0.001). (4) Conclusions: Our findings highlight SyMRI&apos;s reliability in assessing hydrocephalus and intracranial volumes in pediatric cases. Despite some differences from manual measurements, the strong correlation suggests its clinical viability.

Název v anglickém jazyce

Reliability of Automated Intracranial Volume Measurements by Synthetic Brain MRI in Children

Popis výsledku anglicky

(1) Background: Hydrocephalus poses challenges in pediatric neuroimaging, and conventional MRI methods have limitations regarding its accurate quantification. Synthetic MRI (SyMRI) offers a promising automated solution to assess intracranial compartment volumes. However, its clinical utility in pediatric patients remains underexplored. Our study aims to assess the accuracy and reliability of automated CSF volume measurements using SyMRI in children and adolescents, comparing them with manual measurements and human expert ratings. (2) Methods: A single-center retrospective study included 124 pediatric patients undergoing cranial MRI with SyMRI. CSF, brain parenchyma, and intracranial volumes were measured using both automated SyMRI and manual methods. Human radiologists assessed hydrocephalus subjectively. (3) Results: Correlations between manual and SyMRI volume evaluations were significant. Human raters demonstrated good agreement on hydrocephalus ratings among themselves (Fleiss&apos; kappa = 0.66, p &lt; 0.001) but only moderate agreement with the SyMRI method (Cohen&apos;s kappa = 0.45, p &lt; 0.001). SyMRI volumes were systematically tendentially higher in SyMRI (CSF p = 0.005; BPV and ICV p &lt; 0.001). (4) Conclusions: Our findings highlight SyMRI&apos;s reliability in assessing hydrocephalus and intracranial volumes in pediatric cases. Despite some differences from manual measurements, the strong correlation suggests its clinical viability.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Sciences

ISSN

2076-3417

e-ISSN

2076-3417

Svazek periodika

14

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

15

Strana od-do

4751

Kód UT WoS článku

001246937400001

EID výsledku v databázi Scopus

2-s2.0-85195937634