Different cardiac loading conditions and haemodynamic monitoring in animal

Kód výsledku v IS VaVaI

RIV/00216208:11140/12:10109438 - isvavai.cz

Výsledek na webu

http://dx.doi.org/10.4149/BLL_2012_032

DOI - Digital Object Identifier

10.4149/BLL_2012_032

Jazyk výsledku

angličtina

Název v původním jazyce

Different cardiac loading conditions and haemodynamic monitoring in animal

Popis výsledku v původním jazyce

Objective: To develop models of various cardiac loading conditions in an experimental study. Materials and methods: A total of 78 piglets, average weight 24kg were divided into 4 groups under different cardiac loading conditions: Group A were spontaneously breathing pigs without haemodynamic changes, Group B were ventilated animals with increased left ventricular afterload, Group C ventilated with increased right ventricular preload and Group D ventilated with increased afterload of both heart ventricles. Haemodynamic parameters were invasively measured at 60 and 120 minutes. Results: Groups B, C and D demonstrated higher preload of both ventricles, compared with Group A. Group C demonstrated higher preload and afterload of both ventricles in comparison with Groups B and D. Conclusion: Haemodynamic measured data confirmed the expected changes in cardiac loading and corresponded to human clinical situations. These models may be used for future experimental haemodynamic studies.

Název v anglickém jazyce

Different cardiac loading conditions and haemodynamic monitoring in animal

Popis výsledku anglicky

Objective: To develop models of various cardiac loading conditions in an experimental study. Materials and methods: A total of 78 piglets, average weight 24kg were divided into 4 groups under different cardiac loading conditions: Group A were spontaneously breathing pigs without haemodynamic changes, Group B were ventilated animals with increased left ventricular afterload, Group C ventilated with increased right ventricular preload and Group D ventilated with increased afterload of both heart ventricles. Haemodynamic parameters were invasively measured at 60 and 120 minutes. Results: Groups B, C and D demonstrated higher preload of both ventricles, compared with Group A. Group C demonstrated higher preload and afterload of both ventricles in comparison with Groups B and D. Conclusion: Haemodynamic measured data confirmed the expected changes in cardiac loading and corresponded to human clinical situations. These models may be used for future experimental haemodynamic studies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FG - Pediatrie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Z - Vyzkumny zamer (s odkazem do CEZ)
S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bratislavske Lekarske Listy

ISSN

0006-9248

e-ISSN

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Svazek periodika

113

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

4

Strana od-do

133-136

Kód UT WoS článku

000302385900001

EID výsledku v databázi Scopus

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