The Impact of Follicular Fluid Components and Embryo-endometrial Cross-talk on the Oocyte Quality or Embryo Viability: Search for New Biomarkers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F13%3A10144045" target="_blank" >RIV/00216208:11140/13:10144045 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388971:_____/13:00426045

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The Impact of Follicular Fluid Components and Embryo-endometrial Cross-talk on the Oocyte Quality or Embryo Viability: Search for New Biomarkers

Popis výsledku v původním jazyce

To overcome the still insufficient implantation rate following in vitro fertilization (IVF) in humans, more than two embryos are commonly replaced which potentially leads to a high number of multiple pregnancies with associated risks such as low birth weight. The solution for avoiding multiple pregnancies could be optimalization of embryo selection and single embryo transfer. The traditional systems for assessing gamete and embryo viability have limited ability to accurately select those with the best developmental potential. Morphological evaluation remains the primary method of oocyte and embryo assessment during IVF cycles. However, its modest predictive power and inherent inter- and intra-observer variability limits its value. Prolonged embryo culture to blastocyst stage was introduced as a possible strategy for selecting the best embryos but on the other hand the extended period of in vitro culture may have its side effects.

Název v anglickém jazyce

The Impact of Follicular Fluid Components and Embryo-endometrial Cross-talk on the Oocyte Quality or Embryo Viability: Search for New Biomarkers

Popis výsledku anglicky

To overcome the still insufficient implantation rate following in vitro fertilization (IVF) in humans, more than two embryos are commonly replaced which potentially leads to a high number of multiple pregnancies with associated risks such as low birth weight. The solution for avoiding multiple pregnancies could be optimalization of embryo selection and single embryo transfer. The traditional systems for assessing gamete and embryo viability have limited ability to accurately select those with the best developmental potential. Morphological evaluation remains the primary method of oocyte and embryo assessment during IVF cycles. However, its modest predictive power and inherent inter- and intra-observer variability limits its value. Prolonged embryo culture to blastocyst stage was introduced as a possible strategy for selecting the best embryos but on the other hand the extended period of in vitro culture may have its side effects.

Druh

C - Kapitola v odborné knize

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

<a href="/cs/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedicínské centrum Lékařské fakulty v Plzni</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Infertility: Genetic Factors, Treatment Risks and Benefits, Social and Psychological Consequences

ISBN

978-1-62257-909-9

Počet stran výsledku

17

Strana od-do

59-75

Počet stran knihy

153

Název nakladatele

Nova Science Publishers

Místo vydání

New York

Kód UT WoS kapitoly

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