The association of factor V Leiden with various clinical patterns of venous thromboembolism-the factor V Leiden paradox

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10282713" target="_blank" >RIV/00216208:11140/14:10282713 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/14:10282713

Výsledek na webu

<a href="http://dx.doi.org/10.1093/qjmed/hcu055" target="_blank" >http://dx.doi.org/10.1093/qjmed/hcu055</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/qjmed/hcu055" target="_blank" >10.1093/qjmed/hcu055</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The association of factor V Leiden with various clinical patterns of venous thromboembolism-the factor V Leiden paradox

Popis výsledku v původním jazyce

Background: Factor V Leiden (FVL) supposedly carries relatively higher risk of deep vein thrombosis (DVT), compared to the risk of pulmonary embolism (PE). Aim: To prove this paradox in a group of patients with various clinical presentation of venous thromboembolism (VTE). Materials and methods: We retrospectively evaluated clinical pattern of VTE in patients who had been referred to vascular clinic shortly after an acute VTE event. In FVL positive and FVL negative groups we compared the prevalence of isolated symptomatic DVT (proximal or distal) and symptomatic PE with/without DVT, and, moreover, asymptomatic DVT or PE. Results: Of 575 patients (mean age 57 years, 50.1% women), 120 were FVL positive and those had significantly higher prevalence of isolated symptomatic DVT, compared to symptomatic PE with/without DVT. Proximal DVT location was significantly more frequent in FVL carriers. The prevalence of asymptomatic PE did not differ between the two groups. The rate of asymptomatic D

Název v anglickém jazyce

The association of factor V Leiden with various clinical patterns of venous thromboembolism-the factor V Leiden paradox

Popis výsledku anglicky

Background: Factor V Leiden (FVL) supposedly carries relatively higher risk of deep vein thrombosis (DVT), compared to the risk of pulmonary embolism (PE). Aim: To prove this paradox in a group of patients with various clinical presentation of venous thromboembolism (VTE). Materials and methods: We retrospectively evaluated clinical pattern of VTE in patients who had been referred to vascular clinic shortly after an acute VTE event. In FVL positive and FVL negative groups we compared the prevalence of isolated symptomatic DVT (proximal or distal) and symptomatic PE with/without DVT, and, moreover, asymptomatic DVT or PE. Results: Of 575 patients (mean age 57 years, 50.1% women), 120 were FVL positive and those had significantly higher prevalence of isolated symptomatic DVT, compared to symptomatic PE with/without DVT. Proximal DVT location was significantly more frequent in FVL carriers. The prevalence of asymptomatic PE did not differ between the two groups. The rate of asymptomatic D

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

QJM - Monthly Journal of the Association of Physicians

ISSN

1460-2725

e-ISSN

—

Svazek periodika

107

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

715-720

Kód UT WoS článku

000342980900003

EID výsledku v databázi Scopus

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