The Role of 18F-FDG Accumulation and Arterial Enhancement as Biomarkers in the Assessment of Typing, Grading and Staging of Hepatocellular Carcinoma Using 18F-FDG-PET/CT with Integrated Dual-phase CT Angiography

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10294956" target="_blank" >RIV/00216208:11140/15:10294956 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/15:10294956

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The Role of 18F-FDG Accumulation and Arterial Enhancement as Biomarkers in the Assessment of Typing, Grading and Staging of Hepatocellular Carcinoma Using 18F-FDG-PET/CT with Integrated Dual-phase CT Angiography

Popis výsledku v původním jazyce

Aim: The purpose of the present study was to evaluate the possibility of detection, staging and differentiation assessment of hepatocellular carcinoma (HCC) using a combination of dual-phase computed tomography (CT)-angiography in the arterial and portalphase with positron emission tomography (PET) imaging using 18F-fluorodeoxyglucose (18FDG). Patients and Methods: From a set of 10,000 patients who underwent 18FDG-PET/CT, we examined a total of 65 patients (52 males, 13 females; mean age=61.7 years, ranging from 35-82 years) with HCC. The imaging included CT data acquisition after intravenous application of iodinated contrast material in arterial and portal phases, allowed to obtain data in CT angiography quality. Histological diagnosis of the resection sample (21), biopsy (37) or necropsy (7), including the evaluation of the hepatocytary origin of the tumor and the grade of its differentiation, was determined in all patients. Results: The most sensitive sign in the detection of HCC w

Název v anglickém jazyce

The Role of 18F-FDG Accumulation and Arterial Enhancement as Biomarkers in the Assessment of Typing, Grading and Staging of Hepatocellular Carcinoma Using 18F-FDG-PET/CT with Integrated Dual-phase CT Angiography

Popis výsledku anglicky

Aim: The purpose of the present study was to evaluate the possibility of detection, staging and differentiation assessment of hepatocellular carcinoma (HCC) using a combination of dual-phase computed tomography (CT)-angiography in the arterial and portalphase with positron emission tomography (PET) imaging using 18F-fluorodeoxyglucose (18FDG). Patients and Methods: From a set of 10,000 patients who underwent 18FDG-PET/CT, we examined a total of 65 patients (52 males, 13 females; mean age=61.7 years, ranging from 35-82 years) with HCC. The imaging included CT data acquisition after intravenous application of iodinated contrast material in arterial and portal phases, allowed to obtain data in CT angiography quality. Histological diagnosis of the resection sample (21), biopsy (37) or necropsy (7), including the evaluation of the hepatocytary origin of the tumor and the grade of its differentiation, was determined in all patients. Results: The most sensitive sign in the detection of HCC w

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

<a href="/cs/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedicínské centrum Lékařské fakulty v Plzni</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Anticancer Research

ISSN

0250-7005

e-ISSN

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Svazek periodika

35

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GR - Řecká republika

Počet stran výsledku

6

Strana od-do

2241-2246

Kód UT WoS článku

000352731600050

EID výsledku v databázi Scopus

2-s2.0-84928388872