Cutaneous borreliosis associated with T cell-predominant infiltrates: A diagnostic challenge

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10295081" target="_blank" >RIV/00216208:11140/15:10295081 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jaad.2014.12.014" target="_blank" >http://dx.doi.org/10.1016/j.jaad.2014.12.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jaad.2014.12.014" target="_blank" >10.1016/j.jaad.2014.12.014</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cutaneous borreliosis associated with T cell-predominant infiltrates: A diagnostic challenge

Popis výsledku v původním jazyce

Background: With the exception of erythema migrans, Borrelia infection of the skin manifests much more commonly with B cell-rich infiltrates. T cell-rich lesions have rarely been described. Objective: We report a series of 6 patients with cutaneous borreliosis presenting with T cell-predominant skin infiltrates. Methods: We studied the clinicopathologic and molecular features of 6 patients with T cell-rich skin infiltrates. Results: Half of the patients had erythematous patchy, partly annular lesions, and the other patients had features of acrodermatitis chronica atrophicans. Histopathology revealed a dense, band-like or diffuse dermal infiltrate. Apart from small, well differentiated lymphocytes, there were medium-sized lymphocytes with slight nuclearatypia and focal epidermotropism. An interstitial histiocytic component was found in 4 cases, including histiocytic pseudorosettes. Fibrosis was present in all cases but varied in severity and distribution. In 5 patients, borrelia DNA wa

Název v anglickém jazyce

Cutaneous borreliosis associated with T cell-predominant infiltrates: A diagnostic challenge

Popis výsledku anglicky

Background: With the exception of erythema migrans, Borrelia infection of the skin manifests much more commonly with B cell-rich infiltrates. T cell-rich lesions have rarely been described. Objective: We report a series of 6 patients with cutaneous borreliosis presenting with T cell-predominant skin infiltrates. Methods: We studied the clinicopathologic and molecular features of 6 patients with T cell-rich skin infiltrates. Results: Half of the patients had erythematous patchy, partly annular lesions, and the other patients had features of acrodermatitis chronica atrophicans. Histopathology revealed a dense, band-like or diffuse dermal infiltrate. Apart from small, well differentiated lymphocytes, there were medium-sized lymphocytes with slight nuclearatypia and focal epidermotropism. An interstitial histiocytic component was found in 4 cases, including histiocytic pseudorosettes. Fibrosis was present in all cases but varied in severity and distribution. In 5 patients, borrelia DNA wa

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the American Academy of Dermatology

ISSN

0190-9622

e-ISSN

—

Svazek periodika

72

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

683-689

Kód UT WoS článku

000351184200024

EID výsledku v databázi Scopus

2-s2.0-84929509602