Sebaceous carcinoma of the breast: report of four cases and review of the literature

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10296028" target="_blank" >RIV/00216208:11140/15:10296028 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.termedia.pl/Original-paper-Sebaceous-carcinoma-of-the-breast-report-of-four-cases-and-review-of-the-literature,55,25523,1,1.html" target="_blank" >http://www.termedia.pl/Original-paper-Sebaceous-carcinoma-of-the-breast-report-of-four-cases-and-review-of-the-literature,55,25523,1,1.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5114/pjp.2015.53010" target="_blank" >10.5114/pjp.2015.53010</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Sebaceous carcinoma of the breast: report of four cases and review of the literature

Popis výsledku v původním jazyce

Sebaceous carcinoma of the breast is an exceedingly rare neoplasm. Little is known about the behavior and prognosis of this type of breast cancer. We report clinical, histological and immunohistochemical features of four cases of breast carcinoma with prominent (at least 50%) sebaceous differentiation. The tumors occurred in four women, aged 25-66, and were composed of cords, lobules and solid sheets of tumor cells with sebaceous differentiation, comprising 50-90% of the tumor mass. The second componentconsisted of cells with non-vacuolated cytoplasm, present mostly around the periphery of the lobules, or which formed separate tumor sheets with no evidence of sebaceous differentiation and were indistinguishable from a classical ductal carcinoma. Immunohistochemically, three tumors expressed hormone receptors; all cases were HER2-negative and had retained expression of the DNA mismatch repair proteins. Three patients had axillary lymph node metastases, and two patients had distant meta

Název v anglickém jazyce

Sebaceous carcinoma of the breast: report of four cases and review of the literature

Popis výsledku anglicky

Sebaceous carcinoma of the breast is an exceedingly rare neoplasm. Little is known about the behavior and prognosis of this type of breast cancer. We report clinical, histological and immunohistochemical features of four cases of breast carcinoma with prominent (at least 50%) sebaceous differentiation. The tumors occurred in four women, aged 25-66, and were composed of cords, lobules and solid sheets of tumor cells with sebaceous differentiation, comprising 50-90% of the tumor mass. The second componentconsisted of cells with non-vacuolated cytoplasm, present mostly around the periphery of the lobules, or which formed separate tumor sheets with no evidence of sebaceous differentiation and were indistinguishable from a classical ductal carcinoma. Immunohistochemically, three tumors expressed hormone receptors; all cases were HER2-negative and had retained expression of the DNA mismatch repair proteins. Three patients had axillary lymph node metastases, and two patients had distant meta

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polish Journal of Pathology

ISSN

1233-9687

e-ISSN

—

Svazek periodika

66

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

7

Strana od-do

142-148

Kód UT WoS článku

000358822800007

EID výsledku v databázi Scopus

2-s2.0-84938057940