Cervical Lymph node metastasis in high-grade transformation of head and neck adenoid cystic carcinoma: a collective international review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10322794" target="_blank" >RIV/00216208:11140/16:10322794 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s12325-016-0298-5" target="_blank" >http://dx.doi.org/10.1007/s12325-016-0298-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12325-016-0298-5" target="_blank" >10.1007/s12325-016-0298-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cervical Lymph node metastasis in high-grade transformation of head and neck adenoid cystic carcinoma: a collective international review

Popis výsledku v původním jazyce

Adenoid cystic carcinoma (AdCC) is among the most common malignant tumors of the salivary glands. It is characterized by a prolonged clinical course, with frequent local recurrences, late onset of metastases and fatal outcome. High-grade transformation (HGT) is an uncommon phenomenon among salivary carcinomas and is associated with increased tumor aggressiveness. In AdCC with high-grade transformation (AdCC-HGT), the clinical course deviates from the natural history of AdCC. It tends to be accelerated, with a high propensity for lymph node metastasis. In order to shed light on this rare event and, in particular, on treatment implications, we undertook this review: searching for all published cases of AdCC-HGT. We conclude that it is mandatory to perform elective neck dissection in patients with AdCC-HGT, due to the high risk of lymph node metastases associated with transformation.

Název v anglickém jazyce

Cervical Lymph node metastasis in high-grade transformation of head and neck adenoid cystic carcinoma: a collective international review

Popis výsledku anglicky

Adenoid cystic carcinoma (AdCC) is among the most common malignant tumors of the salivary glands. It is characterized by a prolonged clinical course, with frequent local recurrences, late onset of metastases and fatal outcome. High-grade transformation (HGT) is an uncommon phenomenon among salivary carcinomas and is associated with increased tumor aggressiveness. In AdCC with high-grade transformation (AdCC-HGT), the clinical course deviates from the natural history of AdCC. It tends to be accelerated, with a high propensity for lymph node metastasis. In order to shed light on this rare event and, in particular, on treatment implications, we undertook this review: searching for all published cases of AdCC-HGT. We conclude that it is mandatory to perform elective neck dissection in patients with AdCC-HGT, due to the high risk of lymph node metastases associated with transformation.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Advances in Therapy

ISSN

0741-238X

e-ISSN

—

Svazek periodika

33

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

357-368

Kód UT WoS článku

000374258600004

EID výsledku v databázi Scopus

2-s2.0-84958755163