Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10324815" target="_blank" >RIV/00216208:11140/16:10324815 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.anndiagpath.2016.04.006" target="_blank" >http://dx.doi.org/10.1016/j.anndiagpath.2016.04.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.anndiagpath.2016.04.006" target="_blank" >10.1016/j.anndiagpath.2016.04.006</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions
Popis výsledku v původním jazyce
Twenty-one hidradenomas from 20 patients (13 female, 7 male) ranging in age from 18 to 87 years (mean, 57.75 years; median, 60 years) were studied for CRTC1-MAML2 and CRTC3-MAML2 fusions to find out whether there is a correlation between the particular cell type (polyhedral eosinophilic, clear, mucinous, epidermoid, and oncocytic) and presence the above alterations. CRTC1-MAML2 fusions were detected in 10 of the 21 neoplasms (47.6%). Fluorescence in situ hybridization for MAML2 break apart was analyzable in 13 specimens nd in all these specimens was positive, including 4 tumors with no demonstrable CRTC1-MAML2 fusion. n none of the cases was a CRTC3-MAML2 fusion detected. No obvious correlation between the cellular omposition and presence of t(11,19) translocation was found.
Název v anglickém jazyce
Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions
Popis výsledku anglicky
Twenty-one hidradenomas from 20 patients (13 female, 7 male) ranging in age from 18 to 87 years (mean, 57.75 years; median, 60 years) were studied for CRTC1-MAML2 and CRTC3-MAML2 fusions to find out whether there is a correlation between the particular cell type (polyhedral eosinophilic, clear, mucinous, epidermoid, and oncocytic) and presence the above alterations. CRTC1-MAML2 fusions were detected in 10 of the 21 neoplasms (47.6%). Fluorescence in situ hybridization for MAML2 break apart was analyzable in 13 specimens nd in all these specimens was positive, including 4 tumors with no demonstrable CRTC1-MAML2 fusion. n none of the cases was a CRTC3-MAML2 fusion detected. No obvious correlation between the cellular omposition and presence of t(11,19) translocation was found.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FP - Ostatní lékařské obory
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Annals of Diagnostic Pathology
ISSN
1092-9134
e-ISSN
—
Svazek periodika
23
Číslo periodika v rámci svazku
August
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
8-13
Kód UT WoS článku
000380180400002
EID výsledku v databázi Scopus
2-s2.0-84964755821