Rhabdoid Myomelanocytic Tumor (PEComa) of the Ovary: A Clinically Benign Case Followed for 7 Years

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10326980" target="_blank" >RIV/00216208:11140/16:10326980 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1177/1066896916635815" target="_blank" >http://dx.doi.org/10.1177/1066896916635815</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/1066896916635815" target="_blank" >10.1177/1066896916635815</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Rhabdoid Myomelanocytic Tumor (PEComa) of the Ovary: A Clinically Benign Case Followed for 7 Years

Popis výsledku v původním jazyce

A 3.0 x 2.5 cm rhabdoid myomelanocytic tumor was incidentally found in the left ovary of a 43-year-old black woman. The tumor cells were cytologically bland with minimal proliferation rate, multifocally weakly or moderately expressed TFE3, strongly expressed smooth muscle markers and SMARCB1/INI1, and focally expressed HMB45. They contained numerous paranuclear whorls of intermediate filaments that were verified by ultrastructure. No other lines of differentiation were detected within the tumor. Neither translocation nor increased number of copies of the TFE3 gene at Xp11.22 was detected by fluorescence in situ hybridization. The patient remains well, free of tumor, 7 years after surgery. A rhabdoid variant of myomelanocytic tumor is a rarity, with only a single case described previously.

Název v anglickém jazyce

Rhabdoid Myomelanocytic Tumor (PEComa) of the Ovary: A Clinically Benign Case Followed for 7 Years

Popis výsledku anglicky

A 3.0 x 2.5 cm rhabdoid myomelanocytic tumor was incidentally found in the left ovary of a 43-year-old black woman. The tumor cells were cytologically bland with minimal proliferation rate, multifocally weakly or moderately expressed TFE3, strongly expressed smooth muscle markers and SMARCB1/INI1, and focally expressed HMB45. They contained numerous paranuclear whorls of intermediate filaments that were verified by ultrastructure. No other lines of differentiation were detected within the tumor. Neither translocation nor increased number of copies of the TFE3 gene at Xp11.22 was detected by fluorescence in situ hybridization. The patient remains well, free of tumor, 7 years after surgery. A rhabdoid variant of myomelanocytic tumor is a rarity, with only a single case described previously.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Surgical Pathology

ISSN

1066-8969

e-ISSN

—

Svazek periodika

24

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

431-435

Kód UT WoS článku

000379953700010

EID výsledku v databázi Scopus

2-s2.0-84976504088