Breast cancer and Flammer syndrome: any symptoms in common for prediction, prevention and personalised medical approach?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10360440" target="_blank" >RIV/00216208:11140/17:10360440 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/17:10360440

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s13167-017-0089-3" target="_blank" >https://link.springer.com/article/10.1007/s13167-017-0089-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s13167-017-0089-3" target="_blank" >10.1007/s13167-017-0089-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Breast cancer and Flammer syndrome: any symptoms in common for prediction, prevention and personalised medical approach?

Popis výsledku v původním jazyce

An epidemic scale of the breast cancer (BC) prevalence is actually recognised as the reality of the early twentyfirst century. Particularly alarming is that the sporadic BC (about 90% of all patients) creates currently unpredictable subpopulations in terms of disease predisposition, development and progression. Despite broad discussions run since years in BC area, no any plausible approach has been suggested so far to get the overall situation better controlled in the populations. Here, we present highly innovative concepts considering investigation of specific syndromes and symptoms underestimated till now in relationship with BC predisposition and development. Consequently, the purpose of our pilot project was to evaluate the prevalence of Flammer Syndrome (FS) in BC patient cohort. The results achieved here support the main hypothesis of the project clearly demonstrating the tendency of BC patients to the increased prevalence of FS symptoms compared to the disease-free individuals. Our study strongly indicates the relevance of FS symptoms for BC pathology such as feeling inadequately cold, deficient thermoregulation, altered sensitivity to different stimuli, potential dehydration, altered sleep patterns, tendency towards headache,migraine attacks and dizziness. Moreover, the symptoms&apos; appearance is specifically linked to the individual BC subtypes. Potentialmechanisms interconnecting FS with BC pathology are discussed.

Název v anglickém jazyce

Breast cancer and Flammer syndrome: any symptoms in common for prediction, prevention and personalised medical approach?

Popis výsledku anglicky

An epidemic scale of the breast cancer (BC) prevalence is actually recognised as the reality of the early twentyfirst century. Particularly alarming is that the sporadic BC (about 90% of all patients) creates currently unpredictable subpopulations in terms of disease predisposition, development and progression. Despite broad discussions run since years in BC area, no any plausible approach has been suggested so far to get the overall situation better controlled in the populations. Here, we present highly innovative concepts considering investigation of specific syndromes and symptoms underestimated till now in relationship with BC predisposition and development. Consequently, the purpose of our pilot project was to evaluate the prevalence of Flammer Syndrome (FS) in BC patient cohort. The results achieved here support the main hypothesis of the project clearly demonstrating the tendency of BC patients to the increased prevalence of FS symptoms compared to the disease-free individuals. Our study strongly indicates the relevance of FS symptoms for BC pathology such as feeling inadequately cold, deficient thermoregulation, altered sensitivity to different stimuli, potential dehydration, altered sleep patterns, tendency towards headache,migraine attacks and dizziness. Moreover, the symptoms&apos; appearance is specifically linked to the individual BC subtypes. Potentialmechanisms interconnecting FS with BC pathology are discussed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

<a href="/cs/project/LO1503" target="_blank" >LO1503: BIOMEDIC</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

EPMA Journal

ISSN

1878-5077

e-ISSN

—

Svazek periodika

8

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

129-140

Kód UT WoS článku

000405833600005

EID výsledku v databázi Scopus

2-s2.0-85020744478