Biphasic squamoid alveolar papillary renal cell carcinoma: case report and review of the literature

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10365239" target="_blank" >RIV/00216208:11140/17:10365239 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/17:10365239

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Biphasic squamoid alveolar papillary renal cell carcinoma: case report and review of the literature

Popis výsledku v původním jazyce

We describe a case of 45-year-old white woman with multiple cortical adenomas and papillary renal cell carcinomas (PRCC)) in the left kidney, followed by occurrence of multiple ocrtical adenoma, pRCCs, and 2 so-called biphasic squamoid alveolar pRCCs in the right kidney. Biphasic squamoid alveolar PRCC has recently been intrioduced as a new entity. These tumors are characterized by a dual-cell population composed of large eosiophilic squamoid cells and smaller basophilic cells identical to those of type 1 PRCC. Immunohistochemically, all tumor are positive for cytokeratin 7, epithelial membrane antigene, vimentin, and cyclin D1. So far mutliple numerical chromosomal changes have been disclosed by molecular analysisi so far, the most frequent being gains of chromosomes 7 and 17. This review discusses the basic clinical and pathological features of biphasic squamoid alveolar PRCC including historic perspective, biologic behavior, gross and histologic features including immunohistochemistry and molecular genetics, as well as the and differential diagnosis.

Název v anglickém jazyce

Biphasic squamoid alveolar papillary renal cell carcinoma: case report and review of the literature

Popis výsledku anglicky

We describe a case of 45-year-old white woman with multiple cortical adenomas and papillary renal cell carcinomas (PRCC)) in the left kidney, followed by occurrence of multiple ocrtical adenoma, pRCCs, and 2 so-called biphasic squamoid alveolar pRCCs in the right kidney. Biphasic squamoid alveolar PRCC has recently been intrioduced as a new entity. These tumors are characterized by a dual-cell population composed of large eosiophilic squamoid cells and smaller basophilic cells identical to those of type 1 PRCC. Immunohistochemically, all tumor are positive for cytokeratin 7, epithelial membrane antigene, vimentin, and cyclin D1. So far mutliple numerical chromosomal changes have been disclosed by molecular analysisi so far, the most frequent being gains of chromosomes 7 and 17. This review discusses the basic clinical and pathological features of biphasic squamoid alveolar PRCC including historic perspective, biologic behavior, gross and histologic features including immunohistochemistry and molecular genetics, as well as the and differential diagnosis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30109 - Pathology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

AJSP: Review &amp; Reports

ISSN

2381-5949

e-ISSN

—

Svazek periodika

22

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

286-289

Kód UT WoS článku

000424294200003

EID výsledku v databázi Scopus

—