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Pre-surgical Multiparametric Assessment of Breast Lesions Using 3-Tesla Magnetic Resonance

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10366602" target="_blank" >RIV/00216208:11140/17:10366602 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/00669806:_____/17:10366602

  • Výsledek na webu

    <a href="http://dx.doi.org/10.21873/anticanres.12163" target="_blank" >http://dx.doi.org/10.21873/anticanres.12163</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.21873/anticanres.12163" target="_blank" >10.21873/anticanres.12163</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Pre-surgical Multiparametric Assessment of Breast Lesions Using 3-Tesla Magnetic Resonance

  • Popis výsledku v původním jazyce

    Background/Aim: The aim of this study was to evaluate experience with multiparametric breast imaging on 3-Tesla magnetic resonance (3T-MRI) scanner using a dedicated 18-channel coil compared to histological findings in women after surgery. Materials and Methods: The study included 100 women with 105 Breast Imaging Reporting and Data System (BI-RADS) 4 to 6 lesions by mammography who were examined using 3T-MRI and subsequently underwent surgery. MRI included non-contrast T1, T2 and T2 short tau inversion recovery (STIR) sequences, diffusion-weighted imaging with apparent diffusion coeficient maps, postcontrast dynamic study and single-voxel MRI spectroscopy. The results were compared to those of histopathological examination. Results: A sensitivity of 98.68% was found for the whole population, with a specificity of 86.20%. The most valuable findings were diffusion restriction with sensitivity of 90.79% and specificity of 89.66%, and increased choline in the spectrum with sensitivity of 68.42% and specificity of 93.10%. Evaluation of the enhancement curve had sensitivity of 45.05% and specificity of 72.41%. In examination of lymph nodes, 3T-MRI had sensitivity of 92.59% and specificity of 93.87%. Conclusion: Multiparametric 3T-MRI breast imaging shows excellent results in evaluation of breast cancer compared to histological findings, both for primary tumor and nodal metastases. The greatest contribution to improving diagnostic performance is the evaluation of diffusion.

  • Název v anglickém jazyce

    Pre-surgical Multiparametric Assessment of Breast Lesions Using 3-Tesla Magnetic Resonance

  • Popis výsledku anglicky

    Background/Aim: The aim of this study was to evaluate experience with multiparametric breast imaging on 3-Tesla magnetic resonance (3T-MRI) scanner using a dedicated 18-channel coil compared to histological findings in women after surgery. Materials and Methods: The study included 100 women with 105 Breast Imaging Reporting and Data System (BI-RADS) 4 to 6 lesions by mammography who were examined using 3T-MRI and subsequently underwent surgery. MRI included non-contrast T1, T2 and T2 short tau inversion recovery (STIR) sequences, diffusion-weighted imaging with apparent diffusion coeficient maps, postcontrast dynamic study and single-voxel MRI spectroscopy. The results were compared to those of histopathological examination. Results: A sensitivity of 98.68% was found for the whole population, with a specificity of 86.20%. The most valuable findings were diffusion restriction with sensitivity of 90.79% and specificity of 89.66%, and increased choline in the spectrum with sensitivity of 68.42% and specificity of 93.10%. Evaluation of the enhancement curve had sensitivity of 45.05% and specificity of 72.41%. In examination of lymph nodes, 3T-MRI had sensitivity of 92.59% and specificity of 93.87%. Conclusion: Multiparametric 3T-MRI breast imaging shows excellent results in evaluation of breast cancer compared to histological findings, both for primary tumor and nodal metastases. The greatest contribution to improving diagnostic performance is the evaluation of diffusion.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30224 - Radiology, nuclear medicine and medical imaging

Návaznosti výsledku

  • Projekt

    <a href="/cs/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedicínské centrum Lékařské fakulty v Plzni</a><br>

  • Návaznosti

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2017

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Anticancer Research

  • ISSN

    0250-7005

  • e-ISSN

  • Svazek periodika

    37

  • Číslo periodika v rámci svazku

    12

  • Stát vydavatele periodika

    GR - Řecká republika

  • Počet stran výsledku

    6

  • Strana od-do

    6965-6970

  • Kód UT WoS článku

    000417022100058

  • EID výsledku v databázi Scopus

    2-s2.0-85038129390