Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10365228" target="_blank" >RIV/00216208:11140/18:10365228 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/49777513:23520/18:43953579 RIV/00669806:_____/18:10365228
Výsledek na webu
<a href="http://www.sciencedirect.com/science/article/pii/S138824571731146X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S138824571731146X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clinph.2017.10.038" target="_blank" >10.1016/j.clinph.2017.10.038</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia
Popis výsledku v původním jazyce
Objective This study investigated modification in cognitive function following inhalation (IA) and total intravenous (TIVA) anaesthesia measured using auditory ERPs (Event Related Potentials). Methods Auditory ERPs examination with N1, P3a and P3b component registration was carried out one day before surgery (D-1) and on the first (D+1), sixth (D+6) and 42nd (D+42) days after surgery. Results were compared between two anaesthetic groups. Results On D+1, N1 latency was increased in the IA group. A significant reduction was observed in amplitude of the P3a component on D+6, which persisted up to D+42 for both IA and TIVA groups. A reduction in the amplitude of P3b on D+1 with normalization by D+6 was found in both groups as well. Conclusions Intravenous and inhalation anaesthesia lead to similar changes in cognitive function as determined by ERPs, both during the early and late postoperative periods. It cannot be clearly confirmed whether the observed effects are due to anaesthesia or other unmonitored perioperative factors. Significance Post anaesthetic changes represent a subclinical impairment; nevertheless, they represent a potential risk for subsequent development of cognitive difficulties.
Název v anglickém jazyce
Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia
Popis výsledku anglicky
Objective This study investigated modification in cognitive function following inhalation (IA) and total intravenous (TIVA) anaesthesia measured using auditory ERPs (Event Related Potentials). Methods Auditory ERPs examination with N1, P3a and P3b component registration was carried out one day before surgery (D-1) and on the first (D+1), sixth (D+6) and 42nd (D+42) days after surgery. Results were compared between two anaesthetic groups. Results On D+1, N1 latency was increased in the IA group. A significant reduction was observed in amplitude of the P3a component on D+6, which persisted up to D+42 for both IA and TIVA groups. A reduction in the amplitude of P3b on D+1 with normalization by D+6 was found in both groups as well. Conclusions Intravenous and inhalation anaesthesia lead to similar changes in cognitive function as determined by ERPs, both during the early and late postoperative periods. It cannot be clearly confirmed whether the observed effects are due to anaesthesia or other unmonitored perioperative factors. Significance Post anaesthetic changes represent a subclinical impairment; nevertheless, they represent a potential risk for subsequent development of cognitive difficulties.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30103 - Neurosciences (including psychophysiology)
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Clinical Neurophysiology
ISSN
1388-2457
e-ISSN
—
Svazek periodika
129
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
IE - Irsko
Počet stran výsledku
8
Strana od-do
246-253
Kód UT WoS článku
000418602000028
EID výsledku v databázi Scopus
2-s2.0-85037344898