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Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10365228" target="_blank" >RIV/00216208:11140/18:10365228 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/49777513:23520/18:43953579 RIV/00669806:_____/18:10365228

  • Výsledek na webu

    <a href="http://www.sciencedirect.com/science/article/pii/S138824571731146X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S138824571731146X</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.clinph.2017.10.038" target="_blank" >10.1016/j.clinph.2017.10.038</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia

  • Popis výsledku v původním jazyce

    Objective This study investigated modification in cognitive function following inhalation (IA) and total intravenous (TIVA) anaesthesia measured using auditory ERPs (Event Related Potentials). Methods Auditory ERPs examination with N1, P3a and P3b component registration was carried out one day before surgery (D-1) and on the first (D+1), sixth (D+6) and 42nd (D+42) days after surgery. Results were compared between two anaesthetic groups. Results On D+1, N1 latency was increased in the IA group. A significant reduction was observed in amplitude of the P3a component on D+6, which persisted up to D+42 for both IA and TIVA groups. A reduction in the amplitude of P3b on D+1 with normalization by D+6 was found in both groups as well. Conclusions Intravenous and inhalation anaesthesia lead to similar changes in cognitive function as determined by ERPs, both during the early and late postoperative periods. It cannot be clearly confirmed whether the observed effects are due to anaesthesia or other unmonitored perioperative factors. Significance Post anaesthetic changes represent a subclinical impairment; nevertheless, they represent a potential risk for subsequent development of cognitive difficulties.

  • Název v anglickém jazyce

    Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia

  • Popis výsledku anglicky

    Objective This study investigated modification in cognitive function following inhalation (IA) and total intravenous (TIVA) anaesthesia measured using auditory ERPs (Event Related Potentials). Methods Auditory ERPs examination with N1, P3a and P3b component registration was carried out one day before surgery (D-1) and on the first (D+1), sixth (D+6) and 42nd (D+42) days after surgery. Results were compared between two anaesthetic groups. Results On D+1, N1 latency was increased in the IA group. A significant reduction was observed in amplitude of the P3a component on D+6, which persisted up to D+42 for both IA and TIVA groups. A reduction in the amplitude of P3b on D+1 with normalization by D+6 was found in both groups as well. Conclusions Intravenous and inhalation anaesthesia lead to similar changes in cognitive function as determined by ERPs, both during the early and late postoperative periods. It cannot be clearly confirmed whether the observed effects are due to anaesthesia or other unmonitored perioperative factors. Significance Post anaesthetic changes represent a subclinical impairment; nevertheless, they represent a potential risk for subsequent development of cognitive difficulties.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30103 - Neurosciences (including psychophysiology)

Návaznosti výsledku

  • Projekt

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2018

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Clinical Neurophysiology

  • ISSN

    1388-2457

  • e-ISSN

  • Svazek periodika

    129

  • Číslo periodika v rámci svazku

    1

  • Stát vydavatele periodika

    IE - Irsko

  • Počet stran výsledku

    8

  • Strana od-do

    246-253

  • Kód UT WoS článku

    000418602000028

  • EID výsledku v databázi Scopus

    2-s2.0-85037344898