A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10372467" target="_blank" >RIV/00216208:11140/18:10372467 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1097/DAD.0000000000000970" target="_blank" >http://dx.doi.org/10.1097/DAD.0000000000000970</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/DAD.0000000000000970" target="_blank" >10.1097/DAD.0000000000000970</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course

Popis výsledku v původním jazyce

Lymphomatoid papulosis (LyP) type E is a recently delineated variant characterized by the occurrence of large necrotic &quot;eschar&quot;-like lesions displaying microscopically angioinvasive and angiodestructive infiltrates composed of CD30+ lymphocytes, frequently coexpressing CD8. In contrast to other LyP variants where patients develop multiple lesions, most patients with LyP type E present with few lesions (often 1 or 2 at a given time). In this article, we describe a 34-year-old man with LyP type E with an exacerbated clinical course characterized by the occurrence of almost a hundred of lesions. Initially, he presented with a single rapidly growing 2-cm large erythematous nodule on the forearm but after the administration of doxycycline multiple eschar-like lesions developed all over the body. Atypical lymphoid infiltrates with marked angiocentricity and angiotropism of CD30+ mediumsized to large pleomorphic lymphocytes were seen histopathologically. After the withdrawal of the antibiotic, the lesions spontaneously regressed. Awareness of this rare LyP variant and its correct recognition, even if the clinical course is unusual and worrisome, is important to avoid aggressive treatment.

Název v anglickém jazyce

A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course

Popis výsledku anglicky

Lymphomatoid papulosis (LyP) type E is a recently delineated variant characterized by the occurrence of large necrotic &quot;eschar&quot;-like lesions displaying microscopically angioinvasive and angiodestructive infiltrates composed of CD30+ lymphocytes, frequently coexpressing CD8. In contrast to other LyP variants where patients develop multiple lesions, most patients with LyP type E present with few lesions (often 1 or 2 at a given time). In this article, we describe a 34-year-old man with LyP type E with an exacerbated clinical course characterized by the occurrence of almost a hundred of lesions. Initially, he presented with a single rapidly growing 2-cm large erythematous nodule on the forearm but after the administration of doxycycline multiple eschar-like lesions developed all over the body. Atypical lymphoid infiltrates with marked angiocentricity and angiotropism of CD30+ mediumsized to large pleomorphic lymphocytes were seen histopathologically. After the withdrawal of the antibiotic, the lesions spontaneously regressed. Awareness of this rare LyP variant and its correct recognition, even if the clinical course is unusual and worrisome, is important to avoid aggressive treatment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30109 - Pathology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The American Journal of Dermatopathology

ISSN

0193-1091

e-ISSN

—

Svazek periodika

40

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

3

Strana od-do

145-147

Kód UT WoS článku

000441159400015

EID výsledku v databázi Scopus

2-s2.0-85048362399