Regional Collagen Fiber Network in the Articular Disc of the Human Temporomandibular Joint: Biochemical 3-Tesla Quantitative Magnetic Resonance Imaging Compared to Quantitative Histologic Analysis of Fiber Arrangement

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10378784" target="_blank" >RIV/00216208:11140/18:10378784 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.11607/ofph.1879" target="_blank" >http://dx.doi.org/10.11607/ofph.1879</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.11607/ofph.1879" target="_blank" >10.11607/ofph.1879</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Regional Collagen Fiber Network in the Articular Disc of the Human Temporomandibular Joint: Biochemical 3-Tesla Quantitative Magnetic Resonance Imaging Compared to Quantitative Histologic Analysis of Fiber Arrangement

Popis výsledku v původním jazyce

AIMS: To evaluate the regional collagen fiber network in the human temporomandibular joint (TMJ) disc by using biochemical magnetic resonance imaging (MRI) and quantitative histology. METHODS: MRI of 5 heads (10 TMJ discs) obtained from partially dentate or edentulous cadavers was performed at 3-Tesla MRI by using a flexible, 8-channel transmit-receive coil. After MRI, all 10 discs were processed histologically. Percentages of coronal, sagittal, and transverse collagen fibers were assessed stereologically for the anterior, central, and posterior parts of the disc. An anisotropy index was calculated for collagen fiber arrangement in all three regions of interest. RESULTS: In the central part of the TMJ disc, collagen fibers were arranged anisotropically with a preferentially sagittal direction. In the anterior and posterior parts, evidence for fibers being arranged isotropically (randomly) without preferred direction was found. Mean MRI T2 values appeared to be correlated with the anisotropy index of collagen fibers (r = -0.45; P &lt; .05). When tested individually, T2 values of the isotropic anterior and posterior disc regions showed a partial but significant correlation with the anisotropy index of collagen fibers (r = -0.54; P &lt; .05), whereas the anisotropic central part did not (P &gt; .05). CONCLUSION: This study has provided the first systematic comparison of quantitative data on collagen fiber isotropy and anisotropy assessed in histologic sections with biochemical quantitative MRI for human TMJ fibrous cartilage.

Název v anglickém jazyce

Regional Collagen Fiber Network in the Articular Disc of the Human Temporomandibular Joint: Biochemical 3-Tesla Quantitative Magnetic Resonance Imaging Compared to Quantitative Histologic Analysis of Fiber Arrangement

Popis výsledku anglicky

AIMS: To evaluate the regional collagen fiber network in the human temporomandibular joint (TMJ) disc by using biochemical magnetic resonance imaging (MRI) and quantitative histology. METHODS: MRI of 5 heads (10 TMJ discs) obtained from partially dentate or edentulous cadavers was performed at 3-Tesla MRI by using a flexible, 8-channel transmit-receive coil. After MRI, all 10 discs were processed histologically. Percentages of coronal, sagittal, and transverse collagen fibers were assessed stereologically for the anterior, central, and posterior parts of the disc. An anisotropy index was calculated for collagen fiber arrangement in all three regions of interest. RESULTS: In the central part of the TMJ disc, collagen fibers were arranged anisotropically with a preferentially sagittal direction. In the anterior and posterior parts, evidence for fibers being arranged isotropically (randomly) without preferred direction was found. Mean MRI T2 values appeared to be correlated with the anisotropy index of collagen fibers (r = -0.45; P &lt; .05). When tested individually, T2 values of the isotropic anterior and posterior disc regions showed a partial but significant correlation with the anisotropy index of collagen fibers (r = -0.54; P &lt; .05), whereas the anisotropic central part did not (P &gt; .05). CONCLUSION: This study has provided the first systematic comparison of quantitative data on collagen fiber isotropy and anisotropy assessed in histologic sections with biochemical quantitative MRI for human TMJ fibrous cartilage.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30106 - Anatomy and morphology (plant science to be 1.6)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Oral &amp; Facial Pain and Headache

ISSN

2333-0384

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

266-276

Kód UT WoS článku

000444007400006

EID výsledku v databázi Scopus

2-s2.0-85051580457