Secretory carcinoma of the breast: A case report
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F19%3A10393260" target="_blank" >RIV/00216208:11140/19:10393260 - isvavai.cz</a>
Výsledek na webu
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=HCz.5U9.82" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=HCz.5U9.82</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijscr.2019.02.029" target="_blank" >10.1016/j.ijscr.2019.02.029</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Secretory carcinoma of the breast: A case report
Popis výsledku v původním jazyce
WHO has defined the secretory breast carcinoma (SBC) as "a rare, low-grade, translocation-associated invasive carcinoma with a solid, microcystic and tubular architecture composed of cells that produce intracellular and extracellular secretory material "and classed it between "exceptionally rare types and variants "of breast tumors [1]. SBCs account for < 0.15% of all breast cancers [2]. Although it was originally described as a juvenile breast carcinoma, occurring in young children, most cases have been reported in adults of both sexes with the median age of presentation in 25 years [3]. SBC is associated with a characteristic balanced translocation, t(12;15), that creates a ETV6-NTRK3 gene fusion [4-6]. Typically, secretory breast carcinomas are negative for hormone receptors and do not express human epidermal growth factor receptor 2 (HER2) [7]. The breast imaging characteristics of SBC are nonspecific and can mimic benign breast tumor. A definitive diagnosis of SBC is established from histology, immunohistochemistry and cytogenetic evaluation. We present in our study a patient with SBC in line with the SCARE criteria [8].
Název v anglickém jazyce
Secretory carcinoma of the breast: A case report
Popis výsledku anglicky
WHO has defined the secretory breast carcinoma (SBC) as "a rare, low-grade, translocation-associated invasive carcinoma with a solid, microcystic and tubular architecture composed of cells that produce intracellular and extracellular secretory material "and classed it between "exceptionally rare types and variants "of breast tumors [1]. SBCs account for < 0.15% of all breast cancers [2]. Although it was originally described as a juvenile breast carcinoma, occurring in young children, most cases have been reported in adults of both sexes with the median age of presentation in 25 years [3]. SBC is associated with a characteristic balanced translocation, t(12;15), that creates a ETV6-NTRK3 gene fusion [4-6]. Typically, secretory breast carcinomas are negative for hormone receptors and do not express human epidermal growth factor receptor 2 (HER2) [7]. The breast imaging characteristics of SBC are nonspecific and can mimic benign breast tumor. A definitive diagnosis of SBC is established from histology, immunohistochemistry and cytogenetic evaluation. We present in our study a patient with SBC in line with the SCARE criteria [8].
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30109 - Pathology
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
International Journal of Surgery Case Reports
ISSN
2210-2612
e-ISSN
—
Svazek periodika
56
Číslo periodika v rámci svazku
February
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
4
Strana od-do
74-77
Kód UT WoS článku
000461342700020
EID výsledku v databázi Scopus
2-s2.0-85062406792