A very rare case of possible actinomycosis of the mandible from the Middle Ages

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F20%3A10419567" target="_blank" >RIV/00216208:11140/20:10419567 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00094862:_____/20:N0000058 RIV/00216224:14110/20:00116446

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=XQwbenEN6S" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=XQwbenEN6S</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijpp.2020.09.001" target="_blank" >10.1016/j.ijpp.2020.09.001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A very rare case of possible actinomycosis of the mandible from the Middle Ages

Popis výsledku v původním jazyce

Objective: Documented cases of actinomycosis in archaeological skeletons are very rare, especially from Central Europe. Our contribution will help facilitate the differential diagnosis of this disease for other paleopathologists. Material: This paper describes a pathological finding of the skeleton of a 40-year-old male from a burial ground in Sady-S?pitalky (Czech Republic) dated to the 10th-12th century. Methods: The affected skeleton was evaluated as a probable case of actinomycosis on the basis of a detailed macroscopic, X-ray and histological examination. The osteolytic foci examined were compared with similar changes caused by tuberculosis, syphilis and mycoses. Results: The character and location of the defect on the mandible is indicative of organ actinomycosis and is also reflected by the lytic lesion observed on a lumbar vertebra. Conclusions: The described case can be considered one of the very rare paleopathological findings of possible actinomycosis in humans in Central Europe. Significance: Good evidence of bone actinomycosis findings may be beneficial for further paleopathological and epidemiological studies, especially for research focused on the diachronic development of actinomycosis in Europe. In doing so, all available factors, such as hygiene habits, nutrition, social structure and overall health of the population that could be causally related to its origin, course and treatment, can be taken into account. Limitations: The mandible of the studied individual was damaged, especially in the area affected by the lesion, so the paleopathological analysis was difficult to perform. Suggestion for the future research: In future, actinomycosis in this skeleton may be confirmed by bio-molecular analysis.

Název v anglickém jazyce

A very rare case of possible actinomycosis of the mandible from the Middle Ages

Popis výsledku anglicky

Objective: Documented cases of actinomycosis in archaeological skeletons are very rare, especially from Central Europe. Our contribution will help facilitate the differential diagnosis of this disease for other paleopathologists. Material: This paper describes a pathological finding of the skeleton of a 40-year-old male from a burial ground in Sady-S?pitalky (Czech Republic) dated to the 10th-12th century. Methods: The affected skeleton was evaluated as a probable case of actinomycosis on the basis of a detailed macroscopic, X-ray and histological examination. The osteolytic foci examined were compared with similar changes caused by tuberculosis, syphilis and mycoses. Results: The character and location of the defect on the mandible is indicative of organ actinomycosis and is also reflected by the lytic lesion observed on a lumbar vertebra. Conclusions: The described case can be considered one of the very rare paleopathological findings of possible actinomycosis in humans in Central Europe. Significance: Good evidence of bone actinomycosis findings may be beneficial for further paleopathological and epidemiological studies, especially for research focused on the diachronic development of actinomycosis in Europe. In doing so, all available factors, such as hygiene habits, nutrition, social structure and overall health of the population that could be causally related to its origin, course and treatment, can be taken into account. Limitations: The mandible of the studied individual was damaged, especially in the area affected by the lesion, so the paleopathological analysis was difficult to perform. Suggestion for the future research: In future, actinomycosis in this skeleton may be confirmed by bio-molecular analysis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10600 - Biological sciences

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Paleopathology [online]

ISSN

1879-9817

e-ISSN

—

Svazek periodika

31

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

53-59

Kód UT WoS článku

000590591900008

EID výsledku v databázi Scopus

2-s2.0-85090919129