Experimental surgery as part of the development of degradable biomaterials for cardiovascular surgery

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F22%3A10455331" target="_blank" >RIV/00216208:11140/22:10455331 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/22:10455331 RIV/46747885:24510/22:00010674 RIV/68407700:21220/22:00367378

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=S5xrdUISlJ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=S5xrdUISlJ</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33699/PIS.2022.101.12.599-606" target="_blank" >10.33699/PIS.2022.101.12.599-606</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Experimental surgery as part of the development of degradable biomaterials for cardiovascular surgery

Popis výsledku v původním jazyce

Cardiovascular diseases are responsible for significant morbidity and mortality in the population. preclinical testing of each new material is imperative, both in vitro and in vivo, and therefore animal experiments are still a necessary part of the testing process before any clinical use. The aim of this paper is to present the options of using various experimental animal models in the field of cardiovascular surgery including their extrapolation to clinical medicine. An in vivo experiment cannot be avoided in the last phases of cprelinical research of new materials. However, we try to strictly observe the 3R concept - Replacement, Reduction and Refinement; in line with this concept, the potential of each animal should be used as much as possible to reduce the number of animals.

Název v anglickém jazyce

Experimental surgery as part of the development of degradable biomaterials for cardiovascular surgery

Popis výsledku anglicky

Cardiovascular diseases are responsible for significant morbidity and mortality in the population. preclinical testing of each new material is imperative, both in vitro and in vivo, and therefore animal experiments are still a necessary part of the testing process before any clinical use. The aim of this paper is to present the options of using various experimental animal models in the field of cardiovascular surgery including their extrapolation to clinical medicine. An in vivo experiment cannot be avoided in the last phases of cprelinical research of new materials. However, we try to strictly observe the 3R concept - Replacement, Reduction and Refinement; in line with this concept, the potential of each animal should be used as much as possible to reduce the number of animals.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/NU20-02-00368" target="_blank" >NU20-02-00368: Biomechanicky definované vstřebatelné materiály pro kardiovaskulární chirurgii</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Rozhledy v chirurgii

ISSN

0035-9351

e-ISSN

1805-4579

Svazek periodika

101

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

599-606

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85147791308