Survival in gastric and esophageal cancers in the Nordic countries through a half century

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F23%3A10471095" target="_blank" >RIV/00216208:11140/23:10471095 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=aOfiOjapRO" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=aOfiOjapRO</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/cam4.5748" target="_blank" >10.1002/cam4.5748</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Survival in gastric and esophageal cancers in the Nordic countries through a half century

Popis výsledku v původním jazyce

Background: Gastric cancer (GC) and esophageal cancer (EC) are among the most fatal cancers and improving survival in them is a major clinical challenge. Nordic cancer data were recently released up to year 2019. These data are relevant for long- term survival analysis as they originate from high-quality national cancer registries from countries with practically free access to health care, thus documenting &quot;real-world&apos; experience for entire populations.Patients/Methods: Data were obtained for Danish (DK), Finnish (FI), Norwegian (NO), and Swedish (SE) patients from the NORDCAN database from years 1970 through 2019. Relative 1-and 5- year survival were analyzed, and additionally the difference between 1-and 5- year survival was calculated as a measure of trends between years 1 and 5 after diagnosis.Results: Relative 1- year survival for Nordic men and women in GC was 30% in period 1970- 74 and it increased close to 60%. Early 5- year survival ranged be-tween 10 and 15% and the last figures were over 30% for all women and NO men while survival for other men remain below 30%. Survival in EC was below that in GC, and it reached over 50% for 1- year survival only for NO patients; 5- year survival reached over 20% only for NO women. For both cancers, the difference between 1-and 5- year survival increased with time. Survival was worst among old patients.Conclusion: GC and EC survival improved over the 50- year period but the in-crease in 5- year survival was entirely explained by gains in 1- year survival, which improved at an accelerated pace in EC. The likely reasons for improvements are changes in diagnosis, treatment, and care. The challenges are to push survival past year 1 with attention to old patients. These cancers have a potential for pri-mary prevention through the avoidance of risk factors.

Název v anglickém jazyce

Survival in gastric and esophageal cancers in the Nordic countries through a half century

Popis výsledku anglicky

Background: Gastric cancer (GC) and esophageal cancer (EC) are among the most fatal cancers and improving survival in them is a major clinical challenge. Nordic cancer data were recently released up to year 2019. These data are relevant for long- term survival analysis as they originate from high-quality national cancer registries from countries with practically free access to health care, thus documenting &quot;real-world&apos; experience for entire populations.Patients/Methods: Data were obtained for Danish (DK), Finnish (FI), Norwegian (NO), and Swedish (SE) patients from the NORDCAN database from years 1970 through 2019. Relative 1-and 5- year survival were analyzed, and additionally the difference between 1-and 5- year survival was calculated as a measure of trends between years 1 and 5 after diagnosis.Results: Relative 1- year survival for Nordic men and women in GC was 30% in period 1970- 74 and it increased close to 60%. Early 5- year survival ranged be-tween 10 and 15% and the last figures were over 30% for all women and NO men while survival for other men remain below 30%. Survival in EC was below that in GC, and it reached over 50% for 1- year survival only for NO patients; 5- year survival reached over 20% only for NO women. For both cancers, the difference between 1-and 5- year survival increased with time. Survival was worst among old patients.Conclusion: GC and EC survival improved over the 50- year period but the in-crease in 5- year survival was entirely explained by gains in 1- year survival, which improved at an accelerated pace in EC. The likely reasons for improvements are changes in diagnosis, treatment, and care. The challenges are to push survival past year 1 with attention to old patients. These cancers have a potential for pri-mary prevention through the avoidance of risk factors.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

—

Návaznosti

R - Projekt Ramcoveho programu EK

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cancer Medicine

ISSN

2045-7634

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

10212-10221

Kód UT WoS článku

000940470200001

EID výsledku v databázi Scopus

2-s2.0-85149906828