Experimental neurotransplantation for cerebellar ataxias

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F23%3A10471110" target="_blank" >RIV/00216208:11140/23:10471110 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/978-3-031-24345-5_18" target="_blank" >https://doi.org/10.1007/978-3-031-24345-5_18</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-031-24345-5_18" target="_blank" >10.1007/978-3-031-24345-5_18</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Experimental neurotransplantation for cerebellar ataxias

Popis výsledku v původním jazyce

Neurotransplantation is one of the therapeutic methods for cerebellar diseases that are currently being intensively investigated. Despite years of research, there are still many questions to be answered. Compared to transplantation of other tissues and organs, neurotransplantation has some specific challenges, and these are particularly demanding for the cerebellum. In this chapter, the goals of neurotransplantation, its mechanisms underlying graft effects, the types of grafts, as well as the problems of graft survival, differentiation and functional integration are discussed. Different requirements and limitations of neurotransplantation therapy related to different types of pathologies are also discussed. Finally, overview of neurotransplantation research employing animal models of diseases during past decades is provided.

Název v anglickém jazyce

Experimental neurotransplantation for cerebellar ataxias

Popis výsledku anglicky

Neurotransplantation is one of the therapeutic methods for cerebellar diseases that are currently being intensively investigated. Despite years of research, there are still many questions to be answered. Compared to transplantation of other tissues and organs, neurotransplantation has some specific challenges, and these are particularly demanding for the cerebellum. In this chapter, the goals of neurotransplantation, its mechanisms underlying graft effects, the types of grafts, as well as the problems of graft survival, differentiation and functional integration are discussed. Different requirements and limitations of neurotransplantation therapy related to different types of pathologies are also discussed. Finally, overview of neurotransplantation research employing animal models of diseases during past decades is provided.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Trials for Cerebellar Ataxias. From Cellular Models to Human Therapies

ISBN

978-3-031-24344-8

Počet stran výsledku

30

Strana od-do

469-498

Počet stran knihy

727

Název nakladatele

Springer Nature

Místo vydání

Cham

Kód UT WoS kapitoly

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