Histologic Considerations and Salivary Gland Tumor Classification in Surgical Pathology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F23%3A10478821" target="_blank" >RIV/00216208:11140/23:10478821 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/978-3-031-26662-1_11" target="_blank" >https://doi.org/10.1007/978-3-031-26662-1_11</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-031-26662-1_11" target="_blank" >10.1007/978-3-031-26662-1_11</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Histologic Considerations and Salivary Gland Tumor Classification in Surgical Pathology

Popis výsledku v původním jazyce

The classification of salivary gland neoplasms is dynamic and continues to evolve as reflected in the 2022 fifth edition World Health Organization (WHO) Classification of Head and Neck Tumours. A significant contributor to the evolution in the classification of salivary gland tumors is the utilization of molecular testing in their diagnosis and differential diagnosis. Since the fourth edition of the WHO Classification more salivary gland tumors have been shown to harbor tumor type-specific rearrangements resulting in the identification of new types of salivary gland tumors or a delineation of specific subtypes within previously established tumor types. In addition to the tumor types with previously defining molecular alterations including pleomorphic adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma, secretory carcinoma, hyalinizing clear cell carcinoma, epithelial-myoepithelial carcinoma, and myoepithelial carcinoma, more recently molecularly defined tumor types include intraductal carcinoma, microsecretory carcinoma, and mucinous adenocarcinoma. Undoubtedly, molecular testing has significantly contributed to the advances in the diagnosis of salivary gland tumors but the basis in the evaluation of all salivary gland lesions remains their histology supported by immunohistochemical features. This fact is reflected in the WHO classification which is a morphologic-based classification separating neoplastic entities primarily on tumor morphology to predict their biological behavior, albeit buttressed by immunohistochemical staining and molecular testing.

Název v anglickém jazyce

Histologic Considerations and Salivary Gland Tumor Classification in Surgical Pathology

Popis výsledku anglicky

The classification of salivary gland neoplasms is dynamic and continues to evolve as reflected in the 2022 fifth edition World Health Organization (WHO) Classification of Head and Neck Tumours. A significant contributor to the evolution in the classification of salivary gland tumors is the utilization of molecular testing in their diagnosis and differential diagnosis. Since the fourth edition of the WHO Classification more salivary gland tumors have been shown to harbor tumor type-specific rearrangements resulting in the identification of new types of salivary gland tumors or a delineation of specific subtypes within previously established tumor types. In addition to the tumor types with previously defining molecular alterations including pleomorphic adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma, secretory carcinoma, hyalinizing clear cell carcinoma, epithelial-myoepithelial carcinoma, and myoepithelial carcinoma, more recently molecularly defined tumor types include intraductal carcinoma, microsecretory carcinoma, and mucinous adenocarcinoma. Undoubtedly, molecular testing has significantly contributed to the advances in the diagnosis of salivary gland tumors but the basis in the evaluation of all salivary gland lesions remains their histology supported by immunohistochemical features. This fact is reflected in the WHO classification which is a morphologic-based classification separating neoplastic entities primarily on tumor morphology to predict their biological behavior, albeit buttressed by immunohistochemical staining and molecular testing.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30109 - Pathology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

The Milan System for Reporting Salivary Gland Cytopathology

ISBN

978-3-031-26661-4

Počet stran výsledku

7

Strana od-do

229-235

Počet stran knihy

240

Název nakladatele

Springer

Místo vydání

Cham

Kód UT WoS kapitoly

—