Mismatch negativita u závislosti na metamfetaminu: Pilotní studie

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F08%3A00106931" target="_blank" >RIV/00216208:11150/08:00106931 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/08:00001264

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Mismatch negativity in methamphetamine dependence: A pilot study

Popis výsledku v původním jazyce

The objective of this study was to verify hypothesised changes in event related potentials (visual mismatch negativity, v MMN) in 17 subjects dependent on methamphetamine (MAMP) compared to age and gender matched 17 healthy volunteers. We found a significant correlation between vMMN and duration of methamphetamine abuse (Spearman correlation coeficient r=0.54-0.78;P 0.05). The positive correlation indicates drop of originally more negative response to deviant stimulus, what may indicate a pre-attentiveprocessing enhancement in the first years of MAMP abuse with its decease later on. Accordingly, post-hoc analysis revealed significantly stronger vMMN in patients with length of MAMP abuse shorter than 5 years than in paired controls. There were no suchdifferences in abusers with the length of abuse longer than 5 years. The results show that the visual processing on the pre-attentional level can be influenced by long-term MAMP abuse, what can bi specifically assessed by vMMN.

Název v anglickém jazyce

Mismatch negativity in methamphetamine dependence: A pilot study

Popis výsledku anglicky

The objective of this study was to verify hypothesised changes in event related potentials (visual mismatch negativity, v MMN) in 17 subjects dependent on methamphetamine (MAMP) compared to age and gender matched 17 healthy volunteers. We found a significant correlation between vMMN and duration of methamphetamine abuse (Spearman correlation coeficient r=0.54-0.78;P 0.05). The positive correlation indicates drop of originally more negative response to deviant stimulus, what may indicate a pre-attentiveprocessing enhancement in the first years of MAMP abuse with its decease later on. Accordingly, post-hoc analysis revealed significantly stronger vMMN in patients with length of MAMP abuse shorter than 5 years than in paired controls. There were no suchdifferences in abusers with the length of abuse longer than 5 years. The results show that the visual processing on the pre-attentional level can be influenced by long-term MAMP abuse, what can bi specifically assessed by vMMN.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Neurobiologiae Experimentalis

ISSN

0065-1400

e-ISSN

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Svazek periodika

68

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

6

Strana od-do

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Kód UT WoS článku

000255347300012

EID výsledku v databázi Scopus

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