Nestin expression reflects formation, revascularization and reinnervation of new myofibers in regenerating rat hind limb skeletal muscles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F09%3A00208572" target="_blank" >RIV/00216208:11150/09:00208572 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985823:_____/09:00312406

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Nestin expression reflects formation, revascularization and reinnervation of new myofibers in regenerating rat hind limb skeletal muscles

Popis výsledku v původním jazyce

This work provides a comprehensive view of expression and distribution patterns of the intermediate filament nestin in rat regenerating skeletal muscles. In the regenerating skeletal muscle maximal nestin expression was observed in newly formed myoblastsand myotubes and it decreased in the course of the skeletal myofiber development. Furthermore, nestin has been detected in newly formed endothelial cells of blood vessels growing into the regenerated area and later also in peripheral nerves innervatingthe graft, as well as in the host muscle. According to our results, nestin represents an ideal marker for the skeletal muscle regeneration, as its expression reflects processes of development, revascularization and reinnervation of new myofibers.

Název v anglickém jazyce

Nestin expression reflects formation, revascularization and reinnervation of new myofibers in regenerating rat hind limb skeletal muscles

Popis výsledku anglicky

This work provides a comprehensive view of expression and distribution patterns of the intermediate filament nestin in rat regenerating skeletal muscles. In the regenerating skeletal muscle maximal nestin expression was observed in newly formed myoblastsand myotubes and it decreased in the course of the skeletal myofiber development. Furthermore, nestin has been detected in newly formed endothelial cells of blood vessels growing into the regenerated area and later also in peripheral nerves innervatingthe graft, as well as in the host muscle. According to our results, nestin represents an ideal marker for the skeletal muscle regeneration, as its expression reflects processes of development, revascularization and reinnervation of new myofibers.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cells Tissues Organs

ISSN

1422-6405

e-ISSN

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Svazek periodika

189

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

10

Strana od-do

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Kód UT WoS článku

000265178600004

EID výsledku v databázi Scopus

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